Welcome to The Zhao GroupSelected Publications
204. C. Wang, W. Zhong, X. Sun, J. Guo, Y. Chen, Y. Zhao, J. Han, Y. L. Zhao, NIR-activable charge transfer agents for synergistic photoimmunotherapy. Angew. Chem. Int. Ed. 2024, accepted.
203. Y. Liu, H. Zhao, S. Wang, R. Niu, S. Bi, W.-K. Han, Y. Wang, S. Song, H. Zhang, Y. L. Zhao, A Wurster-type covalent organic framework with internal electron transfer-enhanced catalytic capacity for tumor therapy. J. Am. Chem. Soc. 2024, accepted.
202. Y. Cheng, W. Zhong, Y. Chen, B. S. N. Tan, Y. Zhao, J. Guo, M. Ma, Y. L. Zhao, Bimetal-biligand frameworks for spatiotemporal nitric oxide-enhanced sono-immunotherapy. Adv. Mater. 2024, accepted.
201. Q. Huang, C. Ding, W. Wang, L. Yang, Y. Wu, W. Zeng, Z. Li, Z. Shi, L. Mei, X. Zeng, Y. L. Zhao, H. Chen, An “AND” logic gate based supramolecular therapeutic nanoplatform for combatting drug-resistant non-small cell lung cancer. Sci. Adv. 2024, 10, sciadv.adp9071.
200. Y. Liu, H. Zhao, R. Niu, B. Zhang, B. T. G. Lim, S. Song, Y. Wang, H. Zhang, Y. L. Zhao, Single-site nanozyme with exposed unsaturated Cu-O2 sites for tumor therapy by coordinating innate immunity and vasculature normalization. Chem 2024, accepted.
199. Y. Chen, B. S. N. Tan, Y. Cheng, Y. L. Zhao, Artificial polymerizations in living organisms for biomedical applications. Angew. Chem. Int. Ed. 2024, accepted.
198. Z. Li, Q. Yue, H. Zhang, Y. L. Zhao, Methodologies for constructing multi-color room temperature phosphorescent systems. Mater. Today 2024, 78, 209-230.
197. X. Yang, C. Huang, H. Wang, K. Yang, M. Huang, W. Zhang, Q. Yu, H. Wang, L. Zhang, Y. L. Zhao, D. Zhu, Multifunctional nanoparticle loaded injectable alginate hydrogels with deep tumor penetration for enhanced chemo-immunotherapy of cancer. ACS Nano 2024, 18, 18604-18621.
196. C. Zhang, Y. Wu, F. Zeng, Y. Wen, J. Chen, G. Deng, L. Zhang, S. Zhao, S. Wu, Y. L. Zhao, Structurally modulated formation of cyanine J-aggregates with sharp and tunable spectra for multiplexed optoacoustic and fluorescence bioimaging. Angew. Chem. Int. Ed. 2024, 63, e202406694.
195. W. Fang, J. Zhang, M. Guo, Y. L. Zhao, A. C.-H. Sue, Triphenylamine[3]arenes: Streamlining synthesis of a versatile macrocyclic platform for supramolecular architectures and functionalities. Angew. Chem. Int. Ed. 2024, 63, e202409120.
194. Y. Liu, R. Niu, X. Zhang, B. Zhang, X. Chen, J. Guo, S. Song, Y. Wang, H. Zhang, Y. L. Zhao, Metal-organic framework-based nanovaccine for relieving immunosuppressive tumor via hindering efferocytosis of macrophages and promoting pyroptosis and cuproptosis of cancer cells. ACS Nano 2024, 18, 12386-12400.
193. T. He, I. K. W. On, S. Bi, Z. Huang, J. Guo, Z. Wang, Y. L. Zhao, Crystalline olefin-linked chiral covalent organic frameworks as a platform for asymmetric catalysis. Angew. Chem. Int. Ed. 2024, 63, e202405769.
192. W. Zhong, W. Yuan, Y. Chen, Z. Ma, M. Ma, B. S. N. Tan, J. Yang, Y. L. Zhao, Activable nano-immunomodulator assembled from π-extended naphthalenediimide for precision photothermal immunotherapy. Angew. Chem. Int. Ed. 2024, 63, e202401250.
191. B. He, Y. Cao, K. Lin, Y. Wang, Z. Li, Y. Yang, Y. L. Zhao, X. Liu, Strong interactions between Au nanoparticles and BiVO4 photoanode boosts hole extraction for photoelectrochemical water splitting. Angew. Chem. Int. Ed. 2024, 63, e202402435.
190. C. Huang, H. Wang, X. Yang, Q. Yu, H. Wang, L. Zhang, Y. L. Zhao, D. Zhu, Cascade carrier-free nanoparticles forming in situ nanovaccines for synergistic photothermal-immunotherapy of cancer. Adv. Funct. Mater. 2024, 34, 2401489.
189. M. Chang, M. Wang, B. Liu, W. Zhong, D. Jana, Y. Wang, S. Dong, A. Antony, C. Li, Y. Liu, Z. Zhao, J. Lin, W. Jiang, Y. L. Zhao, A cancer nanovaccine based on an FeAl-layered double hydroxide framework for reactive oxygen species-augmented metalloimmunotherapy. ACS Nano 2024, 18, 8143-8156.
188. W. Wang, P. H. Tham, C. Ding, P. Huang, T. Li, J. Luo, H. Xiang, X. Zeng, H. Chen, Y. L. Zhao, Transethosome-based topical administration systems with enhanced penetration and dual actions for treating EGFR-overexpressed cutaneous squamous cell carcinoma. Adv. Funct. Mater. 2024, 34, 2312838.
187. Z. Ma, P. Zeng, T. Zhai, Y. L. Zhao, H. Liang, In situ mitochondrial biomineralization for drug-free cancer therapy. Adv. Mater. 2024, 36, 2310218.
186. J.-R. Wang, K. Song, T.-X. Luan, K. Cheng, Q. Wang, Y. Wang, W. W. Yu, P.-Z. Li, Y. L. Zhao, Robust links in photoactive covalent organic frameworks enable effective photocatalytic reactions under harsh conditions. Nat. Commun. 2024, 15, 1267.
185. X. Wu, Y. Li, M. Wen, Y. Xie, K. Zeng, Y.-N. Liu, W. Chen, Y. L. Zhao, Nanocatalysts for modulating antitumor immunity: fabrications, mechanisms and applications. Chem. Soc. Rev. 2024, 53, 2643-2692.
184. Y. Liu, R. Niu, H. Zhao, Y. Wang, S. Song, H. Zhang, Y. L. Zhao, Single-site nanozymes with a highly conjugated coordination structure for antitumor immunotherapy via cuproptosis and cascade-enhanced T lymphocyte activity. J. Am. Chem. Soc. 2024, 146, 3675-3688.
183. Y. Liu, H. Zhao, Y. L. Zhao, Designing efficient single metal atom biocatalysts at the atomic structure level. Angew. Chem. Int. Ed. 2024, 63, e202315933.
182. S. Meng, H. Du, X. Li, X. Zheng, P. Zhao, Z. Yuan, S. Huang, Y. L. Zhao, L. Dai, An adjuvant micelle-based multifunctional nanosystem for tumor immunotherapy by remodeling three types of immunosuppressive cells. ACS Nano 2024, 18, 3134-3150.
181. B. Mi, Y. Xiong, Y. Zhao, Z. Lin, L. Lu, G. Liu, Y. L. Zhao, Metal–organic framework-integrated composites for bone tissue regeneration. Adv. Funct. Mater. 2024, 34, 2308656.
180. L. Ma, Y. Cheng, X. Feng, X. Zhang, J. Lei, H. Wang, Y. Xu, B. Tong, D. Zhu, D. Wu, X. Zhou, H. Liang, K. Zhao, K. Wang, L. Tan, Y. L. Zhao, C. Yang, A Janus-ROS healing system promoting infectious bone regeneration via sono-epigenetic modulation. Adv. Mater. 2024, 36, 2307846.
179. Z. Li, S. Cao, Y. Zheng, L. Song, H. Zhang, Y. L. Zhao, Colorful ultralong room temperature phosphorescent afterglow with excitation wavelength dependence based on boric acid matrix. Adv. Funct. Mater. 2024, 34, 2306956.
178. Y. Xiong, Q. Feng, L. Lu, X. Qiu, S. Knoedler, A. C. Panayi, D. Jiang, Y. Rinkevich, Z. Lin, B. Mi, G. Liu, Y. L. Zhao, Metal–organic frameworks and their composites for chronic wound healing: from bench to bedside. Adv. Mater. 2024, 36, 2302587.
177. D. Jana, B. He, Y. Chen, J. Liu, Y. L. Zhao, A defect-engineered nanozyme for targeted NIR-II photothermal immunotherapy of cancer. Adv. Mater. 2024, 36, 2206401.
176. W. Yuan, L. Chen, C. Yuan, Z. Zhang, X. Chen, X. Zhang, J. Guo, C. Qian, Z. Zhao, Y. L. Zhao, Cooperative supramolecular polymerization of styrylpyrenes for color-dependent circularly polarized luminescence and photocycloaddition. Nat. Commun. 2023, 14, 8022.
175. C. Qian, W. L. Teo, Q. Gao, H. Wu, Y. Liao, Y. L. Zhao, Polycrystalline covalent organic frameworks. Mater. Today 2023, 71, 91-107.
174. L. Gao, J. Huang, L. Qu, X. Chen, Y. Zhu, C. Li, Q. Tian, Y. L. Zhao, C. Yang, Stepwise taming of triplet excitons via multiple confinements in intrinsic polymers for long-lived room-temperature phosphorescence. Nat. Commun. 2023, 14, 7252.
173. L. Yang, D. Zhang, W. Li, H. Lin, C. Ding, Q. Liu, L. Wang, Z. Li, L. Mei, H. Chen, Y. L. Zhao, X. Zeng, Biofilm microenvironment triggered self-enhancing photodynamic immunomodulatory microneedle for diabetic wound therapy. Nat. Commun. 2023, 14, 7658.
172. Z. Shi, M. Luo, Q. Huang, C. Ding, W. Wang, Y. Wu, J. Luo, C. Lin, T. Chen, X. Zeng, L. Mei, Y. L. Zhao, H. Chen, NIR-dye bridged human serum albumin reassemblies for effective photothermal therapy of tumor. Nat. Commun. 2023, 14, 6567.
171. Y. Dong, S. Dong, C. Yu, J. Liu, S. Gai, Y. Xie, Z. Zhao, X. Qin, L. Feng, P. Yang, Y. L. Zhao, Mitochondria-targeting Cu3VS4 nanostructure with high copper ionic mobility for photothermoelectric therapy. Sci. Adv. 2023, 9, adi9980.
170. S. Wang, T. Wu, S. Wu, J. Guo, T. He, Y. Wu, W. Yuan, Z. Zhang, Y. Hua, Y. L. Zhao, Cobaloxime-integrated covalent organic frameworks for photocatalytic hydrogen evolution coupled with alcohol oxidation. Angew. Chem. Int. Ed. 2023, 62, e202311082.
169. K. Zha, Y. Xiong, W. Zhang, M. Tan, W. Hu, Z. Lin, P. Cheng, L. Lu, K. Cai, B. Mi, Q. Feng, Y. L. Zhao, G. Liu, Waste to wealth: near-infrared/pH dual-responsive copper-humic acid hydrogel films for bacteria-infected cutaneous wound healing. ACS Nano 2023, 17, 17199-17216.
168. Y. Zhao, D. Wang, T. Qian, J. Zhang, Z. Li, Q. Gong, X. Ren, Y. L. Zhao, Biomimetic nanozyme-decorated hydrogels with H2O2-activated oxygenation for modulating immune microenvironment in diabetic wound. ACS Nano 2023, 17, 16854-16869.
167. Y. Chen, M. Zuo, Y. Chen, P. Yu, X. Chen, X. Zhang, W. Yuan, Y. Wu, W. Zhu, Y. L. Zhao, Nanocompartment-confined polymerization in living systems. Nat. Commun. 2023, 14, 5229.
166. C. Qin, X. Wu, L. Tang, X. Chen, M. Li, Y. Mou, B. Su, S. Wang, C. Feng, J. Liu, X. Yuan, Y. L. Zhao, H. Wang, Dual donor-acceptor covalent organic frameworks for hydrogen peroxide photosynthesis. Nat. Commun. 2023, 14, 5238.
165. B. Luo, W. Wang, Y. Zhao, Y. L. Zhao, Hot-electron dynamics mediated medical diagnosis and therapy. Chem. Rev. 2023, 123, 10808-10833.
164. T. He, R. Liu, S. Wang, I. K. W. On, Y. Wu, Y. Xing, W. Yuan, J. Guo, Y. L. Zhao, Bottom-up design of photoactive chiral covalent organic frameworks for visible light-driven asymmetric catalysis. J. Am. Chem. Soc. 2023, 145, 18015-18021.
163. Y. Wu, L. Sun, X. Chen, J. Liu, J. Ouyang, X. Zhang, Y. Guo, Y. Chen, W. Yuan, D. Wang, T. He, F. Zeng, H. Chen, S. Wu, Y. L. Zhao, Cucurbit[8]uril-based water-dispersible assemblies with enhanced optoacoustic performance for multispectral optoacoustic imaging. Nat. Commun. 2023, 14, 3918.
162. K. Zhang, Y. Long, Z. Ma, S. Li, Y. L. Zhao, H. Han, Artificial nanoplatelet regulation of tumor immune microenvironment to inhibit post-surgical tumor recurrence and lung metastasis. Mater. Today 2023, 67, 68-83.
161. D. Wang, J. Liu, C. Wang, W. Zhang, G. Yang, Y. Chen, X. Zhang, Y. Wu, L. Gu, H. Chen, W. Yuan, X. Chen, G. Liu, B. Gao, Q. Chen, Y. L. Zhao, Microbial synthesis of Prussian blue for potentiating checkpoint blockade immunotherapy. Nat. Commun. 2023, 14, 2943.
160. G. Liu, M. G. Humphrey, C. Zhang, Y. L. Zhao, Self-assembled stereomutation with supramolecular chirality inversion. Chem. Soc. Rev. 2023, 52, 4443-4487.
159. Q. Zhou, C. Yang, Y. L. Zhao, Dynamic organic room-temperature phosphorescent systems. Chem 2023, 9, 2446-2480.
158. T. He, Y. L. Zhao, Covalent organic frameworks for energy conversion in photocatalysis. Angew. Chem. Int. Ed. 2023, 62, e202303086.
157. D. Wang, L. Zhang, C. Wang, Z. Cheng, W. Zheng, P. Xu, Q. Chen, Y. L. Zhao, Missing-linker-confined single-atomic Pt nanozymes for enzymatic theranostics of tumor. Angew. Chem. Int. Ed. 2023, 62, e202217995.
156. J. Guo, J. Li, T. Wu, X. Peng, S. Wang, Z. Zhao, Y. Hua, B. Z. Tang, Y. L. Zhao, Free radical-mediated intramolecular photocyclization of AIEgens based on 2,3-diphenylbenzo[b]thiophene S,S-dioxide. J. Am. Chem. Soc. 2023, 145, 7837–7844.
155. T. He, Z. Zhao, R. Liu, X. Liu, B. Ni, Y. Wei, Y. Wu, W. Yuan, H. Peng, Z. Jiang, Y. L. Zhao, Porphyrin-based covalent organic frameworks anchoring Au single atoms for photocatalytic nitrogen fixation. J. Am. Chem. Soc. 2023, 145, 6057-6066.
154. X. Xiong, Y. Chen, Z. Wang, H. Liu, M. Le, C. Lin, G. Wu, L. Wang, X. Shi, Y.-G. Jia, Y. L. Zhao, Polymerizable rotaxane hydrogels for three-dimensional printing fabrication of wearable sensors. Nat. Commun. 2023, 14, 1331.
153. A. K. Bindra, D. Wang, Y. L. Zhao, Metal-organic frameworks meet polymers: from synthesis strategies to healthcare applications. Adv. Mater. 2023, 35, 2300700.
152. L. Feng, R. Zhao, L. Yang, B. Liu, S. Dong, C. Qian, J. Liu, Y. L. Zhao, Tumor-specific NIR-activatable nanoreactor for self-enhanced multimodal imaging and cancer phototherapy. ACS Nano 2023, 17, 1622-1637.
151. X. Shan, W. Chi, H. Jiang, Z. Luo, C. Qian, H. Wu, Y. L. Zhao, Monomer and excimer emission in a conformational and stacking-adaptable molecular system. Angew. Chem. Int. Ed. 2023, 62, e202215652.
150. T.-X. Luan, L. Du, J.-R. Wang, K. Li, Q. Zhang, P.-Z. Li, Y. L. Zhao, Highly effective generation of singlet oxygen by an imidazole-linked robust photosensitizing covalent organic framework. ACS Nano 2022, 16, 21565-21575.
149. M. Guo, J. T. Brewster II, H. Zhang, Y. Zhao, Y. L. Zhao, Challenges and opportunities of chemiresistors based on micro-electro-mechanical systems for chemical olfaction. ACS Nano 2022, 16, 17778-17801.
148. K. Zhang, Z. Ma, S. Li, W. Zhang, M. F. Foda, Y. L. Zhao, H. Han, Platelet-covered nanocarriers for targeted delivery of hirudin to eliminate thrombotic complication in tumor therapy. ACS Nano 2022, 16, 18483-18496.
147. Y. Zhao, S. Song, D. Wang, H. Liu, J. Zhang, Z. Li, J. Wang, X. Ren, Y. L. Zhao, Nanozyme-reinforced hydrogel as a H2O2-driven oxygenerator for enhancing prosthetic interface osseointegration in rheumatoid arthritis therapy. Nat. Commun. 2022, 13, 6758.
146. Y. Yu, Q. Cheng, X. Ji, H. Chen, W. Zeng, X. Zeng, Y. L. Zhao, L. Mei, Engineered drug-loaded cellular membrane nanovesicles for efficient treatment of post-surgical cancer recurrence and metastasis. Sci. Adv. 2022, 8, add3599.
145. M. Chang, Z. Hou, M. Wang, D. Wen, C. Li, Y. Liu, Y. L. Zhao, J. Lin, Cu single atom nanozyme based high-efficiency mild photothermal therapy through cellular metabolic regulation. Angew. Chem. Int. Ed. 2022, 61, e202209245.
144. C. Qian, L. Feng, W. L. Teo, J. Liu, W. Zhou, D. Wang, Y. L. Zhao, Imine and imine-derived linkages in two-dimensional covalent organic frameworks. Nat. Rev. Chem. 2022, 6, 881-898.
143. X. Chen, X. Zhang, Y. Wu, Y. Chen, Y. Guo, D. Jana, D. Wang, W. Yuan, Y. L. Zhao, Tumor extracellular matrix-targeted nanoscavengers reverse suppressive microenvironment for cocktail therapy. Mater. Today 2022, 61, 78-90.
142. Z. Ma, M. Yang, M. F. Foda, K. Zhang, S. Li, H. Liang, Y. L. Zhao, H. Han, Polarization of tumor-associated macrophages promoted by vitamin C-loaded liposomes for cancer immunotherapy. ACS Nano 2022, 16, 17389-17401.
141. C. Ding, C. Chen, X. Zeng, H. Chen, Y. L. Zhao, Emerging strategies in stimuli-responsive prodrug nanosystems for cancer therapy. ACS Nano 2022, 16, 13513-13553.
140. C. You, X. Li, D. Wang, H. Chen, L. Liang, Y. Chen, Y. L. Zhao, H. Xiang, Self-assembled aza-boron-dipyrromethene for ferroptosis-boosted sonodynamic therapy. Angew. Chem. Int. Ed. 2022, 61, e202210174.
139. J. Liu, F. You, B. He, Y. Wu, D. Wang, W. Zhou, C. Qian, G. Yang, G. Liu, H. Wang, Y. Guo, L. Gu, L. Feng, S. Li, Y. L. Zhao, Directing the architecture of surface-clean Cu2O for CO electroreduction. J. Am. Chem. Soc. 2022, 144, 12410-12420.
138. S. Liu, W. Li, H. Chen, J. Zhou, S. Dong, P. Zang, B. Tian, H. Ding, S. Gai, P. Yang, Y. L. Zhao, On-demand generation of peroxynitrite from an integrated two-dimensional system for enhanced tumor therapy. ACS Nano 2022, 16, 8939-8953.
137. L. Dai, M. Yao, Z. Fu, X. Li, X. Zheng, S. Meng, Z. Yuan, K. Cai, H. Yang, Y. L. Zhao, Multifunctional metal-organic framework-based nanoreactor for starvation/oxidation improved indoleamine 2,3-dioxygenase-blockade tumor immunotherapy. Nat. Commun. 2022, 13, 2688.
136. Z. Wang, L. Gao, Y. Zheng, Y. Zhu, Y. Zhang, X. Zheng, C. Wang, Y. Li, Y. L. Zhao, C. Yang, Four-in-one stimulus-responsive long-lived luminescent systems based on pyrene-doped amorphous polymers. Angew. Chem. Int. Ed. 2022, 61, e202203254.
135. J. Guo, C. Yang, Y. L. Zhao, Long-lived organic room-temperature phosphorescence from amorphous polymer systems. Acc. Chem. Res. 2022, 55, 1160-1170.
134. Y. Chen, P. He, D. Jana, D. Wang, M. Wang, P. Yu, W. Zhu, Y. L. Zhao, Glutathione-depleting organic metal adjuvants for effective NIR-II photothermal immunotherapy. Adv. Mater. 2022, 34, 2201706.
133. Y. Zhang, X. Chen, J. Xu, Q. Zhang, L. Gao, Z. Wang, L. Qu, K. Wang, Y. Li, Z. Cai, Y. L. Zhao, C. Yang, Cross-linked polyphosphazene nanospheres boosting long-lived organic room temperature phosphorescence. J. Am. Chem. Soc. 2022, 144, 6107-6117.
132. F. Yang, R. Li, W. Wei, X. Ding, Z. Xu, P. Wang, G. Wang, Y. Xu, H. Fu, Y. L. Zhao, Water-soluble doubly-strapped isolated perylene diimide chromophore. Angew. Chem. Int. Ed. 2022, 61, e202202491.
131. Y. Li, M. Li, L. Liu, C. Xue, Y. Fei, X. Wang, Y. Zhang, K. Cai, Y. L. Zhao, Z. Luo, Cell-specific metabolic reprogramming of tumors for bioactivatable ferroptosis therapy. ACS Nano 2022, 16, 3965-3984.
130. G. Yang, D. Wang, S. Z. F. Phua, A. K. Bindra, C. Qian, R. Zhang, L. Cheng, G. Liu, H. Wu, Z. Liu, Y. L. Zhao, Albumin-based therapeutics capable of glutathione consumption and hydrogen peroxide generation for synergetic chemodynamic and chemotherapy of cancer. ACS Nano 2022, 16, 2319-2329.
129. H. Wang, Y. Yang, X. Yuan, W. L. Teo, Y. Wu, L. Tang, Y. L. Zhao, Structure-performance correlation guided applications of covalent organic frameworks. Mater. Today 2022, 53, 106-133.
128. C. Wang, Y. Zhang, Z. Wang, Y. Zheng, X. Zheng, L. Gao, Q. Zhou, J. Hao, B. Pi, Q. Li, C. Yang, Y. Li, K. Wang, Y. L. Zhao, Photo-induced dynamic room temperature phosphorescence based on triphenyl phosphonium containing polymers. Adv. Funct. Mater. 2022, 32, 2111941.
127. Y. Zhao, S. Song, X. Ren, J. Zhang, Q. Lin, Y. L. Zhao, Supramolecular adhesive hydrogels for tissue engineering applications. Chem. Rev. 2022, 122, 5604-5640.
126. Q. Zhang, M. He, X. Zhang, H. Yu, J. Liu, Y. Guo, J. Zhang, X. Ren, H. Wang, Y. L. Zhao, Tumor microenvironment activated chemodynamic-photodynamic therapy by multistage self-assembly engineered protein nanomedicine. Adv. Funct. Mater. 2022, 32, 2112251.
125. S. Dong, Y. Dong, B. Liu, J. Liu, S. Liu, Z. Zhao, W. Li, B. Tian, R. Zhao, F. He, S. Gai, Y. Xie, P. Yang, Y. L. Zhao, Guiding transition metal-doped hollow cerium tandem nanozymes with elaborately regulated multi-enzymatic activities for intensive chemodynamic therapy. Adv. Mater. 2022, 34, 2107054.
124. A. K. Bindra, S. Sreejith, R. Prasad, M. Gorain, R. Thomas, D. Jana, M. H. Nai, D. Wang, A. Tharayil, G. C. Kundu, R. Srivastava, S. Thomas, C. T. Lim, Y. L. Zhao, A plasmonic supramolecular nanohybrid as a contrast agent for site-selective computed tomography imaging of tumor. Adv. Funct. Mater. 2022, 32, 2110575.
123. J. Chen, L. Chen, Y. Wu, Y. Fang, F. Zeng, S. Wu, Y. L. Zhao, A H2O2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II fluorescent imaging. Nat. Commun. 2021, 12, 6870.
122. L. Gu, W. Ye, X. Liang, A. Lv, H. Ma, M. Singh, W. Jia, Z. Shen, Y. Guo, Y. Gao, H. Chen, D. Wang, Y. Wu, J. Liu, H. Wang, Y.-X. Zheng, Z. An, W. Huang, Y. L. Zhao, Circularly polarized organic room temperature phosphorescence from amorphous copolymers. J. Am. Chem. Soc. 2021, 143, 18527-18535.
121. W. Zhang, J. Liu, X. Li, Y. Zheng, L. Chen, D. Wang, M. F. Foda, Z. Ma, Y. L. Zhao, H. Han, Precise chemodynamic therapy of cancer by trifunctional bacterium-based nanozymes. ACS Nano 2021, 15, 19321-19333.
120. D. Wang, I. W. He, J. Liu, D. Jana, Y. Wu, X. Zhang, C. Qian, Y. Guo, X. Chen, A. K. Bindra, Y. L. Zhao, Missing-linker-assisted artesunate delivery by metal-organic frameworks for synergistic cancer treatment. Angew. Chem. Int. Ed. 2021, 60, 26254-26259.
119. Y. Li, G. V. Baryshnikov, C. Xu, H. Ågren, L. Zhu, T. Yi, Y. L. Zhao, H. Wu, Photoinduced radical emission in a coassembly system. Angew. Chem. Int. Ed. 2021, 60, 23842-23848.
118. D. Wang, Y. L. Zhao, Single-atom engineering of metal-organic frameworks toward healthcare. Chem 2021, 7, 2635-2671.
117. Y. Zhang, Y. Su, H. Wu, Z. Wang, C. Wang, Y. Zheng, X. Zheng, L. Gao, Q. Zhou, Y. Yang, X. Chen, C. Yang, Y. L. Zhao, Large-area, flexible, transparent, and long-lived polymer-based phosphorescence films. J. Am. Chem. Soc. 2021, 143, 13675-13685.
116. Z. Ma, Y. Zhang, X. Dai, W. Zhang, M. F. Foda, J. Zhang, Y. L. Zhao, H. Han, Selective thrombosis of tumor for enhanced hypoxia-activated prodrug therapy. Adv. Mater. 2021, 33, 2104504.
115. Z. Ma, M. F. Foda, H. Liang, Y. L. Zhao, H. Han, In situ nanozyme-amplified NIR-II phototheranostics for tumor-specific imaging and therapy. Adv. Funct. Mater. 2021, 31, 2103765.
114. B. Lu, Y. Bo, M. Yi, Z. Wang, J. Zhang, Z. Zhu, Y. L. Zhao, J. Zhang, Enhancing the solubility and transdermal delivery of drugs using ionic liquid-in-oil microemulsions. Adv. Funct. Mater. 2021, 31, 2102794.
113. Y. Wu, F. Zeng, Y. L. Zhao, S. Wu, Emerging contrast agents for multispectral optoacoustic imaging and their biomedical applications. Chem. Soc. Rev. 2021, 50, 7924-7940.
112. Q. Zhang, J. Zhang, J. Song, Y. Liu, X. Ren, Y. L. Zhao, Protein-based nanomedicine for therapeutic benefits of cancer. ACS Nano 2021, 15, 8001-8038.
111. D. Jana, D. Wang, A. K. Bindra, Y. Guo, J. Liu, Y. L. Zhao, Ultrasmall alloy nanozyme for ultrasound- and near-Infrared light-promoted tumor ablation. ACS Nano 2021, 15, 7774-7782.
110. B. Tian, S. Liu, L. Feng, S. Liu, S. Gai, Y. Dai, L. Xie, B. Liu, P. Yang, Y. L. Zhao, Renal-clearable nickel-doped carbon dots with boosted photothermal conversion efficiency for multimodal imaging-guided cancer therapy in the second near-infrared biowindow. Adv. Funct. Mater. 2021, 31, 2100549.
109. X. Zhang, X. Chen, Y. Guo, G. Gao, D. Wang, Y. Wu, J. Liu, G. Liang, Y. L. Zhao, F.-G. Wu, Dual gate-controlled therapeutics for overcoming bacterium-induced drug resistance and potentiating cancer immunotherapy. Angew. Chem. Int. Ed. 2021, 60, 14013-14021.
108. Y. Zhang, L. Gao, X. Zheng, Z. Wang, C. Yang, H. Tang, L. Qu, Y. Li, Y. L. Zhao, Ultraviolet irradiation-responsive dynamic ultralong organic phosphorescence in polymeric systems. Nat. Commun. 2021, 12, 2297.
107. J. Liang, A. Hao, P. Xing, Y. L. Zhao, Inverse evolution of helicity from molecular to macroscopic level based on N-terminal aromatic amino acids. ACS Nano 2021, 15, 5322-5332.
106. B. He, S. Jia, M. Zhao, Y. Wang, T. Chen, S. Zhao, Z. Li, Z. Lin, Y. L. Zhao, X. Liu, General and robust photothermal heating-enabled high-efficiency photoelectrochemical water splitting. Adv. Mater. 2021, 33, 2004406.
105. Z. Li, X. Liu, G. Wang, B. Li, H. Chen, H. Li, Y. L. Zhao, Photoresponsive supramolecular coordination polyelectrolyte as smart anticounterfeiting inks. Nat. Commun. 2021, 12, 1363.
104. W. L. Teo, W. Zhou, C. Qian, Y. L. Zhao, Industrializing metal-organic frameworks: scalable synthetic means and their transformation into functional materials. Mater. Today 2021, 47, 170-186.
103. H. Xiang, L. Zhao, L. Yu, H. Chen, C. Wei, Y. Chen, Y. L. Zhao, Self-assembled organic nanomedicine enables ultrastable photo-to-heat converting theranostics in the second near infrared biowindow. Nat. Commun. 2021, 12, 218.
102. D. Wang, H. Wu, C. Wang, L. Gu, H. Chen, D. Jana, L. Feng, J. Liu, X. Wang, P. Xu, Z. Guo, Q. Chen, Y. L. Zhao, Self-assembled single-site nanozyme for tumor-specific amplified cascade enzymatic therapy. Angew. Chem. Int. Ed. 2021, 60, 3001-3007.
101. L. Feng, B. Liu, R. Xie, D. Wang, C. Qian, W. Zhou, J. Liu, D. Jana, P. Yang, Y. L. Zhao, An ultrasmall SnFe2O4 nanozyme with endogenous oxygen generation and glutathione depletion for synergistic cancer therapy. Adv. Funct. Mater. 2021, 31, 2006216.
100. C. Qian, W. Zhou, J. Qiao, D. Wang, X. Li, W. L. Teo, X. Shi, H. Wu, J. Di, H. Wang, G. Liu, L. Gu, J. Liu, L. Feng, Y. Liu, S. Y. Quek, K. P. Loh, Y. L. Zhao, Linkage engineering by harnessing supramolecular interactions to fabricate 2D hydrazone-linked covalent organic framework platforms toward advanced catalysis. J. Am. Chem. Soc. 2020, 142, 18138-18149.
99. X. Liu, L. Xiao, J. Weng, Q. Xu, W. Li, C. Zhao, J. Xu, Y. L. Zhao, Regulating the reactivity of black phosphorus via protective chemistry. Sci. Adv. 2020, 6, eabb4359.
98. D. Wang, H. Wu, G. Yang, C. Qian, L. Gu, H. Wang, W. Zhou, J. Liu, Y. Wu, X. Zhang, Z. Guo, H. Chen, D. Jana, Y. L. Zhao, Metal-organic framework derived multicomponent nanoagent as a reactive oxygen species amplifier for enhanced photodynamic therapy. ACS Nano 2020, 14, 13500-13511.
97. Y. Liu, W. Zhou, W. L. Teo, K. Wang, L. Zhang, Y. Zeng, Y. L. Zhao, Covalent-organic-framework-based composite materials. Chem 2020, 6, 3172-3202.
96. X. Zhang, X. Chen, J. Song, J. Zhang, X. Ren, Y. L. Zhao, Size-transformable nanostructures: from design to biomedical applications. Adv. Mater. 2020, 32, 2003752.
95. X. Wang, M. Li, Y. Hou, Y. Li, X. Yao, C. Xue, Y. Fei, Y. Xiang, K. Cai, Y. L. Zhao, Z. Luo, Tumor-microenvironment-activated in situ self-assembly of sequentially responsive biopolymer for targeted photodynamic therapy. Adv. Funct. Mater. 2020, 30, 2000229.
94. D. Wang, D. Jana, Y. L. Zhao, Metal-organic framework derived nanozymes in biomedicine. Acc. Chem. Res. 2020, 53, 1389-1400.
93. X. Wei, D. Zheng, M. Zhao, H. Chen, X. Fan, B. Gao, L. Gu, Y. Guo, J. Qin, J. Wei, Y. L. Zhao, G. Zhang, Cross-linked polyphosphazene hollow nanosphere derived N/P doped porous carbon with single nonprecious metal atoms for oxygen reduction reaction. Angew. Chem. Int. Ed. 2020, 59, 14639-14646.
92. L. Feng, S. Gai, F. He, P. Yang, Y. L. Zhao, Multifunctional bismuth ferrite nanocatalysts with optical and magnetic functions for ultrasound enhanced tumor theranostics. ACS Nano 2020, 14, 7245-7258.
91. Y. Liu, S. Wang, X. Meng, Y. Ye, X. Song, Z. Liang, Y. L. Zhao, Molecular expansion for constructing porous organic polymers with high surface areas and well-defined nanopores. Angew. Chem. Int. Ed. 2020, 59, 19487-19493.
90. G. Zuo, Y. Wang, W. L. Teo, A. Xie, Y. Guo, Y. Dai, W. Zhou, D. Jana, Q. Xian, W. Dong, Y. L. Zhao, Ultrathin ZnIn2S4 nanosheets anchored on Ti3C2Tx MXene for photocatalytic H2 evolution. Angew. Chem. Int. Ed. 2020, 59, 11287-11292.
89. B. Han, Z. Duan, J. Xu, Y. Zhu, Q. Xu, H. Wang, H. Tai, J. Weng, Y. L. Zhao, The art of integrated functionalization: super stable black phosphorus achieved through metal-organic framework coating. Adv. Funct. Mater. 2020, 30, 2002232.
88. C. C. Xue, M. H. Li, Y. Zhao, J. Zhou, Y. Hu, K. Y. Cai, Y. L. Zhao, S. H. Yu, Z. Luo, Tumor microenvironment-activatable Fe-doxorubicin preloaded amorphous CaCO3 nanoformulation triggers ferroptosis in target tumor cells. Sci. Adv. 2020, 6, eaax1346.
87. H. Wang, C. Qian, J. Liu, Y. Zeng, D. Wang, W. Zhou, L. Gu, H. Wu, G. Liu, Y. L. Zhao, Integrating suitable linkage of covalent organic frameworks into covalently bridged inorganic/organic hybrids toward efficient photocatalysis. J. Am. Chem. Soc. 2020, 142, 4862-4871.
86. L. Gu, H. Wu, H. Ma, W. Ye, W. Jia, H. Wang, H. Chen, N. Zhang, D. Wang, C. Qian, Z. An, W. Huang, Y. L. Zhao, Color-tunable ultralong organic room temperature phosphorescence from a multicomponent copolymer. Nat. Commun. 2020, 11, 944.
85. T. Zhang, X. Ma, H. Wu, L. Zhu, Y. L. Zhao, H. Tian, Molecular engineering for metal-free amorphous room-temperature phosphorescent materials. Angew. Chem. Int. Ed. 2020, 59, 11206-11216.
84. Z. Wang, Y. Zhang, C. Wang, X. Zheng, Y. Zheng, L. Gao, C. Yang, Y. Li, L. Qu, Y. L. Zhao, Color-tunable polymeric long-persistent luminescence based on polyphosphazenes. Adv. Mater. 2020, 32, 1907355.
83. D. Wang, H. Wu, S. Z. F. Phua, G. Yang, W. Q. Lim, L. Gu, C. Qian, H. Wang, Z. Guo, H. Chen, Y. L. Zhao, Self-assembled single-atom nanozyme form enhanced photodynamic therapy treatment of tumor. Nat. Commun. 2020, 11, 357.
82. L. Zhao, J. Li, Y. Su, L. Yang, L. Chen, L. Qiang, Y. Wang, H. Xiang, H. P. Tham, J. Peng, Y. L. Zhao, MTH1 inhibitor amplifies the lethality of reactive oxygen species to tumor in photodynamic therapy. Sci. Adv. 2020, 6, eaaz0575.
81. Y. Su, Y. Zhang, Z. Wang, W. Gao, P. Jia, D. Zhang, C. Yang, Y. Li, Y. L. Zhao, Excitation-dependent long-life luminescent polymeric systems under ambient conditions. Angew. Chem. Int. Ed. 2020, 59, 9967-9971.
80. L. Sun, Y. Zhuang, Y. Yuan, W. Zhan, X. J. Wang, X. Han, Y. L. Zhao, Nitrogen-doped carbon-coated CuO-In2O3 p-n heterojunction for remarkable photocatalytic hydrogen evolution. Adv. Energy Mater. 2019, 9, 1902839.
79. Y. Zhai, G. Liu, F. Jin, Y. Zhang, X. Gong, Z. Miao, J. Li, M. Zhang, Y. Cui, L. Zhang, Y. Liu, H. Zhang, Y. L. Zhao, Y. Zeng, Construction of covalent-organic frameworks (COFs) from amorphous covalent organic polymers via linkage replacement. Angew. Chem. Int. Ed. 2019, 58, 17679-17683.
78. W. Cheng, X. Zeng, H. Chen, Z. Li, W. Zeng, L. Mei, Y. L. Zhao, Versatile polydopamine platforms: synthesis and promising applications for surface modification and advanced nanomedicine. ACS Nano 2019, 13, 8537-8565.
77. Y. Wang, S. Z. F. Phua, G. Dong, X. Liu, B. He, Q. Zhai, Y. Li, C. Zheng, H. Quan, Z. Li, Y. L. Zhao, Structure tuning of polymeric carbon nitride for solar energy conversion: from nano to molecular scale. Chem 2019, 5, 2775-2813.
76. H. Wu, Z. Chen, W. Chi, B. A. Kaur, L. Gu, C. Qian, B. Wu, B. Yue, G. Liu, G. Yang, L. Zhu, Y. L. Zhao, Structural engineering of luminogens with high emission efficiency both in solution and the solid state. Angew. Chem. Int. Ed. 2019, 58, 11419-11423.
75. P. Xing, Y. Li, S. Xue, S. Z. F. Phua, C. Ding, H. Chen, Y. L. Zhao, Occurrence of chiral nanostructures induced by multiple hydrogen bonds. J. Am. Chem. Soc. 2019, 141, 9946-9954.
74. G. Liu, C. Zhou, W. L. Teo, C. Qian, Y. L. Zhao, Self-sorting double-network hydrogels with tunable supramolecular handedness and mechanical property. Angew. Chem. Int. Ed. 2019, 58, 9366-9372.
73. H. Wu, Y. L. Zhao, Colour-tunable ultralong emission. Nat. Photonics 2019, 13, 373-375.
72. D. Wang, H. Wu, W. Q. Lim, S. Z. F. Phua, P. Xu, Q. Chen, Z. Guo, Y. L. Zhao, A mesoporous nanoenzyme derived from metal-organic frameworks with endogenous oxygen generation to alleviate tumor hypoxia for significantly enhanced photodynamic therapy. Adv. Mater. 2019, 31, 1901893.
71. L. Sun, R. Li, W. Zhan, Y. Yuan, X. Wang, X. Han, Y. L. Zhao, Double-shelled hollow rods assembled from nitrogen/sulfur-codoped carbon coated indium oxide nanoparticles as excellent photocatalysts. Nat. Commun. 2019, 10, 2270.
70. G. Yang, S. Z. F. Phua, W. Q. Lim, R. Zhang, L. Feng, G. Liu, H. Wu, A. K. Bindra, D. Jana, Z. Liu, Y. L. Zhao, A hypoxia-responsive albumin-based nanosystem for deep tumor penetration and excellent therapeutic efficacy. Adv. Mater. 2019, 31, 1901513.
69. H. Chen, X. Zeng, H. P. Tham, S. Z. F. Phua, W. Cheng, W. Zeng, H. Shi, L. Mei, Y. L. Zhao, NIR-light-activated combination therapy with a precise ratio of photosensitizer and prodrug using a host-guest strategy. Angew. Chem. Int. Ed. 2019, 58, 7641-7646.
68. S. Z. F. Phua, G. Yang, W. Q. Lim, A. Verma, H. Chen, T. Thanabalu, Y. L. Zhao, Catalase integrated hyaluronic acid as nanocarriers for enhanced photodynamic therapy in solid tumor. ACS Nano 2019, 13, 4742-4751.
67. Z. Miao, G. Liu, Y. Cui, Z. Liu, J. Li, F. Han, Y. Liu, X. Sun, X. Gong, Y. Zhai, Y. L. Zhao, Y. Zeng, A novel strategy for construction of covalent organic frameworks from nonporous covalent organic polymers. Angew. Chem. Int. Ed. 2019, 58, 4906-4910.
66. G. Yang, S. Z. F. Phua, A. K. Bindra, Y. L. Zhao, Degradability and clearance of inorganic nanoparticles for biomedical applications. Adv. Mater. 2019, 31, 1805730.
65. H. Wu, W. Chi, Z. Chen, G. Liu, L. Gu, A. K. Bindra, G. Yang, X. Liu, Y. L. Zhao, Achieving amorphous ultralong room temperature phosphorescence by coassembling planar small organic molecules with polyvinyl alcohol. Adv. Funct. Mater. 2019, 29, 1807243.
64. G. Liu, J. Sheng, W. L. Teo, G. Yang, H. Wu, Y. Li, Y. L. Zhao, Control on dimensions and supramolecular chirality of self-assemblies through light and metal ions. J. Am. Chem. Soc. 2018, 140, 16275-16283.
63. H. P. Tham, K. Xu, W. Q. Lim, H. Chen, M. Zheng, T. G. S. Thng, S. S. Venkatraman, C. Xu, Y. L. Zhao, Microneedle-assisted topical delivery of photodynamically active mesoporous formulation for combination therapy of deep-seated melanoma. ACS Nano 2018, 12, 11936-11948.
62. L. Zhao, W. Yuan, J. Li, L. Yang, Y. Su, J. Peng, R. Chen, H. P. Tham, H. Chen, W. Q. Lim, H. Xiang, P. Xing, F. Li, Y. L. Zhao, Independent of EPR effect: a smart delivery nanosystem for tracking and treatment of nonvascularized intra-abdominal metastases. Adv. Funct. Mater. 2018, 28, 1806162.
61. P. Xing, S. Z. F. Phua, X. Wei, Y. L. Zhao, Programmable multicomponent self-assembly based on aromatic amino acids. Adv. Mater. 2018, 30, 1805175.
60. P. Xing, Y. L. Zhao, Controlling supramolecular chirality in multicomponent self-assembled systems. Acc. Chem. Res. 2018, 51, 2324-2334.
59. P. Xing, C. Yang, Y. Wang, S. Z. F. Phua, Y. L. Zhao, Solvent-controlled assembly of aromatic glutamic dendrimers for efficient luminescent color conversion. Adv. Funct. Mater. 2018, 28, 1802859.
58. Z. Liu, H. Zhang, Y. L. Zhao, Pillararene-based self-assembled amphiphiles. Chem. Soc. Rev. 2018, 47, 5491-5528.
57. G. Liu, J. Sheng, H. Wu, C. Yang, G. Yang, Y. Li, R. Ganguly, L. Zhu, Y. L. Zhao, Controlling supramolecular chirality of two-component hydrogels by J- and H-aggregation of building blocks. J. Am. Chem. Soc. 2018, 140, 6467-6473.
56. Y. Su, S. Z. F. Phua, Y. Li, X. Zhou, D. Jana, G. Liu, W. Q. Lim, W. K. Ong, C. Yang, Y. L. Zhao, Ultralong room temperature phosphorescence from amorphous organic materials toward confidential information encryption and decryption. Sci. Adv. 2018, 4, eaas9732.
55. P. Xing, Y. Li, Y. Wang, P. Z. Li, H. Chen, S. Z. F. Phua, Y. L. Zhao, Water binding mediated gelation/crystallization and thermosensitive superchirality. Angew. Chem. Int. Ed. 2018, 57, 7774-7779.
54. X. Zhang, Z. Luo, P. Yu, Y. Cai, Y. Du, D. Wu, S. Gao, C. Tan, Z. Li, M. Ren, T. Osipowicz, S. Chen, Z. Jiang, J. Li, Y. Huang, J. Yang, Y. Chen, C. Y. Ang, Y. L. Zhao, P. Wang, L. Song, X. Wu, Z. Liu, A. Borgna, H. Zhang, Lithiation-induced amorphization of Pd3P2S8 for highly efficient hydrogen evolution. Nat. Catal. 2018, 1, 460-468.
53. Y. Wang, X. Liu, J. Liu, B. Han, X. Hu, F. Yang, Z. Xu, Y. Li, S. Jia, Z. Li, Y. L. Zhao, Carbon quantum dot implanted graphite carbon nitride nanotubes: excellent charge separation and enhanced photocatalytic hydrogen evolution. Angew. Chem. Int. Ed. 2018, 57, 5765-5771.
52. P. Xing, H. Chen, H. Xiang, Y. L. Zhao, Selective co-assembly of aromatic amino acids to fabricate hydrogels with light irradiation induced emission for fluorescent imprint. Adv. Mater. 2018, 30, 1705633.
51. G. Liu, X. Li, J. Sheng, P. Z. Li, W. K. Ong, S. Z. F. Phua, H. Agren, L. Zhu, Y. L. Zhao, Helicity inversion of supramolecular hydrogels induced by achiral substituents. ACS Nano 2017, 11, 11880-11889.
50. C. Tan, L. Zhao, P. Yu, Y. Huang, B. Chen, Z. Lai, X. Qi, M. H. Goh, X. Zhang, S. Han, X. J. Wu, Z. Liu, Y. L. Zhao, H. Zhang, Preparation of ultrathin two-dimensional TixTa1-xSyOz nanosheets as highly efficient photothermal agents. Angew. Chem. Int. Ed. 2017, 56, 7842-7846.
49. J. Liang, Z. Liang, R. Zou, Y. L. Zhao, Heterogeneous catalysis in zeolites, mesoporous silica, and metal-organic frameworks. Adv. Mater. 2017, 29, 1701139.
48. P. Xing, P. Li, H. Chen, A. Hao, Y. L. Zhao, Understanding pathway complexity of organic micro/nanofiber growth in hydrogen bonded co-assembly of aromatic amino acids. ACS Nano 2017, 11, 4206-4216.
47. X. Yao, Y. L. Zhao, Three-dimensional porous graphene networks and hybrids for lithium-ion battery and supercapacitors. Chem 2017, 2, 171-200.
46. P. Xing, Y. L. Zhao, Multifunctional nanoparticles self-assembled from small organic building blocks for biomedicine. Adv. Mater. 2016, 28, 7304-7339.
45. T. Feng, X. Ai, G. An, P. Yang, Y. L. Zhao, Charge-convertible carbon dots for imaging-guided drug delivery with enhanced in vivo cancer therapeutic efficiency. ACS Nano 2016, 10, 4410-4420.
44. P. Z. Li, X. J. Wang, J. Liu, J. S. Lim, R. Zou, Y. L. Zhao, A trazole-containing metal-organic framework as a highly effective and substrate size-dependent catalyst for CO2 conversion. J. Am. Chem. Soc. 2016, 138, 2142-2145.
43. P. Xing, H. Chen, L. Bai, A. Hao, Y. L. Zhao, Superstructure formation and topological evolution achieved by self-organization of a highly adaptive dynamer. ACS Nano 2016, 10, 2716-2727.
42. L. Zhao, W. Yuan, C. Y. Ang, Q. Qu, Y. Dai, Y. Gao, Z. Luo, J. G. Wang, H. Chen, M. Li, F. Li, Y. L. Zhao, Silica-polymer hybrid with self-assembled PEG corona excreted rapidly via a hepatobiliary route. Adv. Funct. Mater. 2016, 26, 3036-3047.
41. Y. Zeng, R. Zou, Y. L. Zhao, Covalent organic frameworks for CO2 capture. Adv. Mater. 2016, 28, 2855-2873.
40. L. Bai, Y. L. Zhao, Interlocked moelcules - aqueous assembly. Nat. Chem. 2015, 7, 944-945.
39. K. T. Nguyen, Y. L. Zhao, Engineering hybrid nanoparticles for on-demand diagnostics and therapeutics. Acc. Chem. Res. 2015, 48, 3016-3025.
38. P. Z. Li, X. J. Wang, S. Y. Tan, C. Y. Ang, H. Chen, J. Liu, R. Zou, Y. L. Zhao, Clicked isoreticular metal-organic frameworks and their high performance on selective capture and separation of large organic molecules. Angew. Chem. Int. Ed. 2015, 54, 12748-12752.
37. M. Li, C. Teh, C. Y. Ang, S. Y. Tan, Z. Luo, Q. Qu, Y. Zhang, V. Korzh, Y. L. Zhao, Near-infrared light-absorptive stealth liposomes for localized photothermal ablation of tumors combined with chemotherapy. Adv. Funct. Mater. 2015, 25, 5602-5610.
36. P. Borah, S. Sreejith, P. Anees, N. V. Menon, Y. Kang, A. Ajayaghosh, Y. L. Zhao, Near-IR squaraine dye-loaded gated periodic mesoporous organosilica for photo-oxidation of phenol in continuous-flow device. Sci. Adv. 2015, 1, e1500390.
35. S. Sreejith, J. Joseph, M. Lin, N. V. Menon, P. Borah, H. J. Ng, Y. X. Loong, Y. Kang, S. W. K. Yu, Y. L. Zhao, Near-infrared squaraine dye encapsulated micelles for in vivo fluorescence and photoacoustic bimodal imaging. ACS Nano 2015, 9, 5695-5704.
34. A. K. Mandal, S. Sreejith, T. He, S. K. Maji, X. J. Wang, S. L. Ong, J. Joseph, H. Sun, Y. L. Zhao, Three photon-excited luminescence from unsymmetrical cyanostilbene aggregates: morphology tuning and targeted bioimaging. ACS Nano 2015, 9, 4796-4805.
33. X. Ma, Y. L. Zhao, Biomedical applications of supramolecular systems based on host-guest interactions. Chem. Rev. 2015, 115, 7794-7839.
32. Y. Zeng, R. Zou, Z. Luo, H. Zhang, X. Yao, R. Zou, Y. L. Zhao, Covalent organic frameworks formed with two types of covalent bonds based on orthogonal reactions. J. Am. Chem. Soc. 2015, 137, 1020-1023.
31. Y. Zhao, Z. Luo, M. Li, Q. Qu, X. Ma, S. H. Yu, Y. L. Zhao, A preloaded amorphous calcium carbonate-doxorubicin@silica nanoreactor for pH-responsive delivery of anticancer drug. Angew. Chem. Int. Ed. 2015, 54, 919-922.
30. S. K. Maji, S. Sreejith, J. Joseph, M. Lin, T. He, Y. Tong, H. Sun, S. W. K. Yu, Y. L. Zhao, Upconversion nanoparticles as a contrast agent for photoacoustic imaging in live mice. Adv. Mater. 2014, 26, 5633-5638.
29. A. Jana, K. T. Nguyen, X. Li, P. Zhu, N. S. Tan, H. Agren, Y. L. Zhao, Perylene-derived single-component organic nanoparticles with tunable emission: efficient anticancer drug carriers with real-time monitoring of drug release. ACS Nano 2014, 8, 5939-5952.
28. H. Shi, X. Ma, Q. Zhao, B. Liu, Q. Qu, Z. An, Y. L. Zhao, W. Huang, Ultrasmall phosphorescent polymer dots for ratiometric oxygen sensing and photodynamic cancer therapy. Adv. Funct. Mater. 2014, 24, 4823-4830.
27. Q. Zhang, X. Wang, P. Z. Li, K. T. Nguyen, X. J. Wang, Z. Luo, H. Zhang, N. S. Tan, Y. L. Zhao, Biocompatible, uniform, and redispersible mesoporous silica nanoparticles for cancer-targeting drug delivery in vivo. Adv. Funct. Mater. 2014, 24, 2450-2461.
26. Z. Luo, X. Ding, Y. Hu, S. Wu, Y. Xiang, Y. Zeng, B. Zhang, H. Yan, H. Zhang, L. Zhu, J. Liu, J. Li, K. Cai, Y. L. Zhao, Engineering a hollow nanocontainer platform with multifunctional molecular machines for tumor-targeted therapy in vitro and in vivo. ACS Nano 2013, 7, 10271-10284.
25. H. Zhang, X. Ma, K. T. Nguyen, Y. L. Zhao, Biocompatible pillararene-assembly-based carriers for dual bioimaging. ACS Nano 2013, 7, 7853-7863.
24. L. Zhu, X. Li, S. Wu, K. T. Nguyen, H. Yan, H. Agren, Y. L. Zhao, Chirality control in in-situ preparation of gold nanoparticle superstructures directed by a coordinatable organogelator. J. Am. Chem. Soc. 2013, 135, 9174-9180.
23. L. Zhu, X. Li, Q. Zhang, X. Ma, M. Li, H. Zhang, Z. Luo, H. Agren, Y. L. Zhao, Unimolecular photoconversion of multicolor luminescence on hierarchical self-assemblies. J. Am. Chem. Soc. 2013, 135, 5175-5182.
22. H. Li, C. Cheng, P. R. McGonigal, A. C. Fahrenbach, M. Frasconi, W. G. Liu, Z. Zhu, Y. L. Zhao, C. Ke, J. Lei, R. M. Young, S. M. Dyar, D. T. Co, Y. W. Yang, Y. Y. Botros, W. A. Goddard, M. R. Wasielewski, R. D. Astumian, J. F. Stoddart, Relative unidirectional translation in an artificial molecular assembly fueled by light. J. Am. Chem. Soc. 2013, 135, 18609-18620.
21. H. Li, Z. Zhu, A. C. Fahrenbach, B. M. Savoie, C. Ke, J. C. Barnes, J. Lei, Y. L. Zhao, L. M. Lilley, T. J. Marks, M. A. Ratner, J. F. Stoddart, Mechanical bond-induced radical stabilization. J. Am. Chem. Soc. 2013, 135, 456-467.
20. S. Sreejith, X. Ma, Y. L. Zhao, Graphene oxide wrapping on squaraine-loaded mesoporous silica nanoparticles for bioimaging. J. Am. Chem. Soc. 2012, 134, 17346-17349.
19. Q. Zhang, F. Liu, K. T. Nguyen, X. Ma, X. Wang, B. Xing, Y. L. Zhao, Multifunctional mesoporous silica nanoparticles for cancer-targeted and controlled drug delivery. Adv. Funct. Mater. 2012, 22, 5144-5156.
18. H. Yan, C. Teh, S. Sreejith, L. Zhu, A. Kwok, W. Fang, X. Ma, K. T. Nguyen, V. Korzh, Y. L. Zhao, Functional mesoporous silica nanoparticles for photothermal-controlled drug delivery in vivo. Angew. Chem. Int. Ed. 2012, 51, 8373-8377.
17. P. Borah, X. Ma, K. T. Nguyen, Y. L. Zhao, A vanadyl complex grafted to periodic mesoporous organosilica: a green catalyst for selective hydroxylation of benzene to phenol. Angew. Chem. Int. Ed. 2012, 51, 7756-7761.
16. L. Zhu, C. Y. Ang, X. Li, K. T. Nguyen, S. Y. Tan, H. Agren, Y. L. Zhao, Luminescent color conversion on cyanostilbene functionalized quantum dots via in-situ photo-tuning. Adv. Mater. 2012, 24, 4020-4024.
15. C. Wang, Z. Li, D. Cao, Y. L. Zhao, J. W. Gaines, O. A. Bozdemir, M. W. Ambrogio, M. Frasconi, Y. Y. Botros, J. I. Zink, J. F. Stoddart, Stimulated release of size-selected cargos in succession from mesoporous silica nanoparticles. Angew. Chem. Int. Ed. 2012, 51, 5460-5465.
14. M. W. Ambrogio, C. R. Thomas, Y. L. Zhao, J. I. Zink, J. F. Stoddart, Mechanized silica nanoparticles: a new frontier in theranostic nanomedicine. Acc. Chem. Res. 2011, 44, 903-913.
13. H. Li, A. C. Fahrenbach, A. Coskun, Z. Zhu, G. Barin, Y. L. Zhao, Y. Y. Botros, J. P. Sauvage, J. F. Stoddart, A light-stimulated moelcular switch driven by radical-radical interactions in water. Angew. Chem. Int. Ed. 2011, 50, 6782-6788.
12. Y. L. Zhao, Z. Li, S. Kabehie, Y. Y. Botros, J. F. Stoddart, J. I. Zink, pH-Operated nanopistons on the surfaces of mesoporous silica nanoparticles. J. Am. Chem. Soc. 2010, 132, 13016-13025.
11. H. Meng, M. Xue, T. Xia, Y. L. Zhao, S. Kabehie, F. Tamanoi, J. F. Stoddart, J. I. Zink, A. E. Nel, Autonomous in vitro anticancer drug release from mesoporous silica nanoparticles derivatized with pH-sensitive supramolecular nanovalves. J. Am. Chem. Soc. 2010, 132, 12690-12697.
10. Y. L. Zhao, J. F. Stoddart, Noncovalent functionalization of single-walled carbon nanotubes. Acc. Chem. Res. 2009, 42, 1161-1171.
9. Q. Li, W. Zhang, Q. S. Mijanic, C. H. Sue, Y. L. Zhao, L. Liu, C. Knobler, J. F. Stoddart, O. M. Yaghi, Docking in metal-organic frameworks. Science 2009, 325, 855-859.
8. D. Ferris, Y. L. Zhao, N. M. Khashab, H. A. Khatib, J. F. Stoddart, J. I. Zink, Light-operated mechanized nanoparticles. J. Am. Chem. Soc. 2009, 131, 1686-1688.
7. Y. L. Zhao, L. Hu, G. Gruner, J. F. Stoddart, A tunable photosensor. J. Am. Chem. Soc. 2008, 130, 16996-17003.
6. Y. L. Zhao, W. R. Dichtel, A. Trabolsi, S. Saha, I. Aprahamian, J. F. Stoddart, A redox-switchable alpha-cyclodextrin-based [2]rotaxane. J. Am. Chem. Soc. 2008, 130, 11294-11296.
5. Y. L. Zhao, I. Aprahamian, A. Trabolsi, N. Erina, J. F. Stoddart, Organogel formation by a cholesterol-stoppered bistable [2]rotaxane and its dumbbell precusor. J. Am. Chem. Soc. 2008, 130, 6348-6350.
4. Y. L. Zhao, L. Hu, J. F. Stoddart, G. Gruner, Pyrenecyclodextrin-decorated single-walled carbon nanotube field-effect transistor as chemical sensor. Adv. Mater. 2008, 20, 1910-1915.
3. L. Hu, Y. L. Zhao, K. Ryu, C. Zhou, J. F. Stoddart, G. Gruner, Light-induced charge transfer in CdSe-SWNT hybrids. Adv. Mater. 2008, 20, 939-946.
2. Y. Liu, L. Yu, Y. Chen, Y. L. Zhao, H. Yang, Construction and DNA condensation of cyclodextrin-based polypseudorotaxanes with anthryl grafts. J. Am. Chem. Soc. 2007, 129, 10656-10657.
1. Y. Liu, Y. L. Zhao, H. Y. Zhang, H. B. Song, Polymeric rotaxane constructed from the inclusion complex of beta-cyclodextrin and 4,4'-dipyridine by coordination with Ni(II) ions. Angew. Chem. Int. Ed. 2003, 42, 3260-3263.
204. C. Wang, W. Zhong, X. Sun, J. Guo, Y. Chen, Y. Zhao, J. Han, Y. L. Zhao, NIR-activable charge transfer agents for synergistic photoimmunotherapy. Angew. Chem. Int. Ed. 2024, accepted.
203. Y. Liu, H. Zhao, S. Wang, R. Niu, S. Bi, W.-K. Han, Y. Wang, S. Song, H. Zhang, Y. L. Zhao, A Wurster-type covalent organic framework with internal electron transfer-enhanced catalytic capacity for tumor therapy. J. Am. Chem. Soc. 2024, accepted.
202. Y. Cheng, W. Zhong, Y. Chen, B. S. N. Tan, Y. Zhao, J. Guo, M. Ma, Y. L. Zhao, Bimetal-biligand frameworks for spatiotemporal nitric oxide-enhanced sono-immunotherapy. Adv. Mater. 2024, accepted.
201. Q. Huang, C. Ding, W. Wang, L. Yang, Y. Wu, W. Zeng, Z. Li, Z. Shi, L. Mei, X. Zeng, Y. L. Zhao, H. Chen, An “AND” logic gate based supramolecular therapeutic nanoplatform for combatting drug-resistant non-small cell lung cancer. Sci. Adv. 2024, 10, sciadv.adp9071.
200. Y. Liu, H. Zhao, R. Niu, B. Zhang, B. T. G. Lim, S. Song, Y. Wang, H. Zhang, Y. L. Zhao, Single-site nanozyme with exposed unsaturated Cu-O2 sites for tumor therapy by coordinating innate immunity and vasculature normalization. Chem 2024, accepted.
199. Y. Chen, B. S. N. Tan, Y. Cheng, Y. L. Zhao, Artificial polymerizations in living organisms for biomedical applications. Angew. Chem. Int. Ed. 2024, accepted.
198. Z. Li, Q. Yue, H. Zhang, Y. L. Zhao, Methodologies for constructing multi-color room temperature phosphorescent systems. Mater. Today 2024, 78, 209-230.
197. X. Yang, C. Huang, H. Wang, K. Yang, M. Huang, W. Zhang, Q. Yu, H. Wang, L. Zhang, Y. L. Zhao, D. Zhu, Multifunctional nanoparticle loaded injectable alginate hydrogels with deep tumor penetration for enhanced chemo-immunotherapy of cancer. ACS Nano 2024, 18, 18604-18621.
196. C. Zhang, Y. Wu, F. Zeng, Y. Wen, J. Chen, G. Deng, L. Zhang, S. Zhao, S. Wu, Y. L. Zhao, Structurally modulated formation of cyanine J-aggregates with sharp and tunable spectra for multiplexed optoacoustic and fluorescence bioimaging. Angew. Chem. Int. Ed. 2024, 63, e202406694.
195. W. Fang, J. Zhang, M. Guo, Y. L. Zhao, A. C.-H. Sue, Triphenylamine[3]arenes: Streamlining synthesis of a versatile macrocyclic platform for supramolecular architectures and functionalities. Angew. Chem. Int. Ed. 2024, 63, e202409120.
194. Y. Liu, R. Niu, X. Zhang, B. Zhang, X. Chen, J. Guo, S. Song, Y. Wang, H. Zhang, Y. L. Zhao, Metal-organic framework-based nanovaccine for relieving immunosuppressive tumor via hindering efferocytosis of macrophages and promoting pyroptosis and cuproptosis of cancer cells. ACS Nano 2024, 18, 12386-12400.
193. T. He, I. K. W. On, S. Bi, Z. Huang, J. Guo, Z. Wang, Y. L. Zhao, Crystalline olefin-linked chiral covalent organic frameworks as a platform for asymmetric catalysis. Angew. Chem. Int. Ed. 2024, 63, e202405769.
192. W. Zhong, W. Yuan, Y. Chen, Z. Ma, M. Ma, B. S. N. Tan, J. Yang, Y. L. Zhao, Activable nano-immunomodulator assembled from π-extended naphthalenediimide for precision photothermal immunotherapy. Angew. Chem. Int. Ed. 2024, 63, e202401250.
191. B. He, Y. Cao, K. Lin, Y. Wang, Z. Li, Y. Yang, Y. L. Zhao, X. Liu, Strong interactions between Au nanoparticles and BiVO4 photoanode boosts hole extraction for photoelectrochemical water splitting. Angew. Chem. Int. Ed. 2024, 63, e202402435.
190. C. Huang, H. Wang, X. Yang, Q. Yu, H. Wang, L. Zhang, Y. L. Zhao, D. Zhu, Cascade carrier-free nanoparticles forming in situ nanovaccines for synergistic photothermal-immunotherapy of cancer. Adv. Funct. Mater. 2024, 34, 2401489.
189. M. Chang, M. Wang, B. Liu, W. Zhong, D. Jana, Y. Wang, S. Dong, A. Antony, C. Li, Y. Liu, Z. Zhao, J. Lin, W. Jiang, Y. L. Zhao, A cancer nanovaccine based on an FeAl-layered double hydroxide framework for reactive oxygen species-augmented metalloimmunotherapy. ACS Nano 2024, 18, 8143-8156.
188. W. Wang, P. H. Tham, C. Ding, P. Huang, T. Li, J. Luo, H. Xiang, X. Zeng, H. Chen, Y. L. Zhao, Transethosome-based topical administration systems with enhanced penetration and dual actions for treating EGFR-overexpressed cutaneous squamous cell carcinoma. Adv. Funct. Mater. 2024, 34, 2312838.
187. Z. Ma, P. Zeng, T. Zhai, Y. L. Zhao, H. Liang, In situ mitochondrial biomineralization for drug-free cancer therapy. Adv. Mater. 2024, 36, 2310218.
186. J.-R. Wang, K. Song, T.-X. Luan, K. Cheng, Q. Wang, Y. Wang, W. W. Yu, P.-Z. Li, Y. L. Zhao, Robust links in photoactive covalent organic frameworks enable effective photocatalytic reactions under harsh conditions. Nat. Commun. 2024, 15, 1267.
185. X. Wu, Y. Li, M. Wen, Y. Xie, K. Zeng, Y.-N. Liu, W. Chen, Y. L. Zhao, Nanocatalysts for modulating antitumor immunity: fabrications, mechanisms and applications. Chem. Soc. Rev. 2024, 53, 2643-2692.
184. Y. Liu, R. Niu, H. Zhao, Y. Wang, S. Song, H. Zhang, Y. L. Zhao, Single-site nanozymes with a highly conjugated coordination structure for antitumor immunotherapy via cuproptosis and cascade-enhanced T lymphocyte activity. J. Am. Chem. Soc. 2024, 146, 3675-3688.
183. Y. Liu, H. Zhao, Y. L. Zhao, Designing efficient single metal atom biocatalysts at the atomic structure level. Angew. Chem. Int. Ed. 2024, 63, e202315933.
182. S. Meng, H. Du, X. Li, X. Zheng, P. Zhao, Z. Yuan, S. Huang, Y. L. Zhao, L. Dai, An adjuvant micelle-based multifunctional nanosystem for tumor immunotherapy by remodeling three types of immunosuppressive cells. ACS Nano 2024, 18, 3134-3150.
181. B. Mi, Y. Xiong, Y. Zhao, Z. Lin, L. Lu, G. Liu, Y. L. Zhao, Metal–organic framework-integrated composites for bone tissue regeneration. Adv. Funct. Mater. 2024, 34, 2308656.
180. L. Ma, Y. Cheng, X. Feng, X. Zhang, J. Lei, H. Wang, Y. Xu, B. Tong, D. Zhu, D. Wu, X. Zhou, H. Liang, K. Zhao, K. Wang, L. Tan, Y. L. Zhao, C. Yang, A Janus-ROS healing system promoting infectious bone regeneration via sono-epigenetic modulation. Adv. Mater. 2024, 36, 2307846.
179. Z. Li, S. Cao, Y. Zheng, L. Song, H. Zhang, Y. L. Zhao, Colorful ultralong room temperature phosphorescent afterglow with excitation wavelength dependence based on boric acid matrix. Adv. Funct. Mater. 2024, 34, 2306956.
178. Y. Xiong, Q. Feng, L. Lu, X. Qiu, S. Knoedler, A. C. Panayi, D. Jiang, Y. Rinkevich, Z. Lin, B. Mi, G. Liu, Y. L. Zhao, Metal–organic frameworks and their composites for chronic wound healing: from bench to bedside. Adv. Mater. 2024, 36, 2302587.
177. D. Jana, B. He, Y. Chen, J. Liu, Y. L. Zhao, A defect-engineered nanozyme for targeted NIR-II photothermal immunotherapy of cancer. Adv. Mater. 2024, 36, 2206401.
176. W. Yuan, L. Chen, C. Yuan, Z. Zhang, X. Chen, X. Zhang, J. Guo, C. Qian, Z. Zhao, Y. L. Zhao, Cooperative supramolecular polymerization of styrylpyrenes for color-dependent circularly polarized luminescence and photocycloaddition. Nat. Commun. 2023, 14, 8022.
175. C. Qian, W. L. Teo, Q. Gao, H. Wu, Y. Liao, Y. L. Zhao, Polycrystalline covalent organic frameworks. Mater. Today 2023, 71, 91-107.
174. L. Gao, J. Huang, L. Qu, X. Chen, Y. Zhu, C. Li, Q. Tian, Y. L. Zhao, C. Yang, Stepwise taming of triplet excitons via multiple confinements in intrinsic polymers for long-lived room-temperature phosphorescence. Nat. Commun. 2023, 14, 7252.
173. L. Yang, D. Zhang, W. Li, H. Lin, C. Ding, Q. Liu, L. Wang, Z. Li, L. Mei, H. Chen, Y. L. Zhao, X. Zeng, Biofilm microenvironment triggered self-enhancing photodynamic immunomodulatory microneedle for diabetic wound therapy. Nat. Commun. 2023, 14, 7658.
172. Z. Shi, M. Luo, Q. Huang, C. Ding, W. Wang, Y. Wu, J. Luo, C. Lin, T. Chen, X. Zeng, L. Mei, Y. L. Zhao, H. Chen, NIR-dye bridged human serum albumin reassemblies for effective photothermal therapy of tumor. Nat. Commun. 2023, 14, 6567.
171. Y. Dong, S. Dong, C. Yu, J. Liu, S. Gai, Y. Xie, Z. Zhao, X. Qin, L. Feng, P. Yang, Y. L. Zhao, Mitochondria-targeting Cu3VS4 nanostructure with high copper ionic mobility for photothermoelectric therapy. Sci. Adv. 2023, 9, adi9980.
170. S. Wang, T. Wu, S. Wu, J. Guo, T. He, Y. Wu, W. Yuan, Z. Zhang, Y. Hua, Y. L. Zhao, Cobaloxime-integrated covalent organic frameworks for photocatalytic hydrogen evolution coupled with alcohol oxidation. Angew. Chem. Int. Ed. 2023, 62, e202311082.
169. K. Zha, Y. Xiong, W. Zhang, M. Tan, W. Hu, Z. Lin, P. Cheng, L. Lu, K. Cai, B. Mi, Q. Feng, Y. L. Zhao, G. Liu, Waste to wealth: near-infrared/pH dual-responsive copper-humic acid hydrogel films for bacteria-infected cutaneous wound healing. ACS Nano 2023, 17, 17199-17216.
168. Y. Zhao, D. Wang, T. Qian, J. Zhang, Z. Li, Q. Gong, X. Ren, Y. L. Zhao, Biomimetic nanozyme-decorated hydrogels with H2O2-activated oxygenation for modulating immune microenvironment in diabetic wound. ACS Nano 2023, 17, 16854-16869.
167. Y. Chen, M. Zuo, Y. Chen, P. Yu, X. Chen, X. Zhang, W. Yuan, Y. Wu, W. Zhu, Y. L. Zhao, Nanocompartment-confined polymerization in living systems. Nat. Commun. 2023, 14, 5229.
166. C. Qin, X. Wu, L. Tang, X. Chen, M. Li, Y. Mou, B. Su, S. Wang, C. Feng, J. Liu, X. Yuan, Y. L. Zhao, H. Wang, Dual donor-acceptor covalent organic frameworks for hydrogen peroxide photosynthesis. Nat. Commun. 2023, 14, 5238.
165. B. Luo, W. Wang, Y. Zhao, Y. L. Zhao, Hot-electron dynamics mediated medical diagnosis and therapy. Chem. Rev. 2023, 123, 10808-10833.
164. T. He, R. Liu, S. Wang, I. K. W. On, Y. Wu, Y. Xing, W. Yuan, J. Guo, Y. L. Zhao, Bottom-up design of photoactive chiral covalent organic frameworks for visible light-driven asymmetric catalysis. J. Am. Chem. Soc. 2023, 145, 18015-18021.
163. Y. Wu, L. Sun, X. Chen, J. Liu, J. Ouyang, X. Zhang, Y. Guo, Y. Chen, W. Yuan, D. Wang, T. He, F. Zeng, H. Chen, S. Wu, Y. L. Zhao, Cucurbit[8]uril-based water-dispersible assemblies with enhanced optoacoustic performance for multispectral optoacoustic imaging. Nat. Commun. 2023, 14, 3918.
162. K. Zhang, Y. Long, Z. Ma, S. Li, Y. L. Zhao, H. Han, Artificial nanoplatelet regulation of tumor immune microenvironment to inhibit post-surgical tumor recurrence and lung metastasis. Mater. Today 2023, 67, 68-83.
161. D. Wang, J. Liu, C. Wang, W. Zhang, G. Yang, Y. Chen, X. Zhang, Y. Wu, L. Gu, H. Chen, W. Yuan, X. Chen, G. Liu, B. Gao, Q. Chen, Y. L. Zhao, Microbial synthesis of Prussian blue for potentiating checkpoint blockade immunotherapy. Nat. Commun. 2023, 14, 2943.
160. G. Liu, M. G. Humphrey, C. Zhang, Y. L. Zhao, Self-assembled stereomutation with supramolecular chirality inversion. Chem. Soc. Rev. 2023, 52, 4443-4487.
159. Q. Zhou, C. Yang, Y. L. Zhao, Dynamic organic room-temperature phosphorescent systems. Chem 2023, 9, 2446-2480.
158. T. He, Y. L. Zhao, Covalent organic frameworks for energy conversion in photocatalysis. Angew. Chem. Int. Ed. 2023, 62, e202303086.
157. D. Wang, L. Zhang, C. Wang, Z. Cheng, W. Zheng, P. Xu, Q. Chen, Y. L. Zhao, Missing-linker-confined single-atomic Pt nanozymes for enzymatic theranostics of tumor. Angew. Chem. Int. Ed. 2023, 62, e202217995.
156. J. Guo, J. Li, T. Wu, X. Peng, S. Wang, Z. Zhao, Y. Hua, B. Z. Tang, Y. L. Zhao, Free radical-mediated intramolecular photocyclization of AIEgens based on 2,3-diphenylbenzo[b]thiophene S,S-dioxide. J. Am. Chem. Soc. 2023, 145, 7837–7844.
155. T. He, Z. Zhao, R. Liu, X. Liu, B. Ni, Y. Wei, Y. Wu, W. Yuan, H. Peng, Z. Jiang, Y. L. Zhao, Porphyrin-based covalent organic frameworks anchoring Au single atoms for photocatalytic nitrogen fixation. J. Am. Chem. Soc. 2023, 145, 6057-6066.
154. X. Xiong, Y. Chen, Z. Wang, H. Liu, M. Le, C. Lin, G. Wu, L. Wang, X. Shi, Y.-G. Jia, Y. L. Zhao, Polymerizable rotaxane hydrogels for three-dimensional printing fabrication of wearable sensors. Nat. Commun. 2023, 14, 1331.
153. A. K. Bindra, D. Wang, Y. L. Zhao, Metal-organic frameworks meet polymers: from synthesis strategies to healthcare applications. Adv. Mater. 2023, 35, 2300700.
152. L. Feng, R. Zhao, L. Yang, B. Liu, S. Dong, C. Qian, J. Liu, Y. L. Zhao, Tumor-specific NIR-activatable nanoreactor for self-enhanced multimodal imaging and cancer phototherapy. ACS Nano 2023, 17, 1622-1637.
151. X. Shan, W. Chi, H. Jiang, Z. Luo, C. Qian, H. Wu, Y. L. Zhao, Monomer and excimer emission in a conformational and stacking-adaptable molecular system. Angew. Chem. Int. Ed. 2023, 62, e202215652.
150. T.-X. Luan, L. Du, J.-R. Wang, K. Li, Q. Zhang, P.-Z. Li, Y. L. Zhao, Highly effective generation of singlet oxygen by an imidazole-linked robust photosensitizing covalent organic framework. ACS Nano 2022, 16, 21565-21575.
149. M. Guo, J. T. Brewster II, H. Zhang, Y. Zhao, Y. L. Zhao, Challenges and opportunities of chemiresistors based on micro-electro-mechanical systems for chemical olfaction. ACS Nano 2022, 16, 17778-17801.
148. K. Zhang, Z. Ma, S. Li, W. Zhang, M. F. Foda, Y. L. Zhao, H. Han, Platelet-covered nanocarriers for targeted delivery of hirudin to eliminate thrombotic complication in tumor therapy. ACS Nano 2022, 16, 18483-18496.
147. Y. Zhao, S. Song, D. Wang, H. Liu, J. Zhang, Z. Li, J. Wang, X. Ren, Y. L. Zhao, Nanozyme-reinforced hydrogel as a H2O2-driven oxygenerator for enhancing prosthetic interface osseointegration in rheumatoid arthritis therapy. Nat. Commun. 2022, 13, 6758.
146. Y. Yu, Q. Cheng, X. Ji, H. Chen, W. Zeng, X. Zeng, Y. L. Zhao, L. Mei, Engineered drug-loaded cellular membrane nanovesicles for efficient treatment of post-surgical cancer recurrence and metastasis. Sci. Adv. 2022, 8, add3599.
145. M. Chang, Z. Hou, M. Wang, D. Wen, C. Li, Y. Liu, Y. L. Zhao, J. Lin, Cu single atom nanozyme based high-efficiency mild photothermal therapy through cellular metabolic regulation. Angew. Chem. Int. Ed. 2022, 61, e202209245.
144. C. Qian, L. Feng, W. L. Teo, J. Liu, W. Zhou, D. Wang, Y. L. Zhao, Imine and imine-derived linkages in two-dimensional covalent organic frameworks. Nat. Rev. Chem. 2022, 6, 881-898.
143. X. Chen, X. Zhang, Y. Wu, Y. Chen, Y. Guo, D. Jana, D. Wang, W. Yuan, Y. L. Zhao, Tumor extracellular matrix-targeted nanoscavengers reverse suppressive microenvironment for cocktail therapy. Mater. Today 2022, 61, 78-90.
142. Z. Ma, M. Yang, M. F. Foda, K. Zhang, S. Li, H. Liang, Y. L. Zhao, H. Han, Polarization of tumor-associated macrophages promoted by vitamin C-loaded liposomes for cancer immunotherapy. ACS Nano 2022, 16, 17389-17401.
141. C. Ding, C. Chen, X. Zeng, H. Chen, Y. L. Zhao, Emerging strategies in stimuli-responsive prodrug nanosystems for cancer therapy. ACS Nano 2022, 16, 13513-13553.
140. C. You, X. Li, D. Wang, H. Chen, L. Liang, Y. Chen, Y. L. Zhao, H. Xiang, Self-assembled aza-boron-dipyrromethene for ferroptosis-boosted sonodynamic therapy. Angew. Chem. Int. Ed. 2022, 61, e202210174.
139. J. Liu, F. You, B. He, Y. Wu, D. Wang, W. Zhou, C. Qian, G. Yang, G. Liu, H. Wang, Y. Guo, L. Gu, L. Feng, S. Li, Y. L. Zhao, Directing the architecture of surface-clean Cu2O for CO electroreduction. J. Am. Chem. Soc. 2022, 144, 12410-12420.
138. S. Liu, W. Li, H. Chen, J. Zhou, S. Dong, P. Zang, B. Tian, H. Ding, S. Gai, P. Yang, Y. L. Zhao, On-demand generation of peroxynitrite from an integrated two-dimensional system for enhanced tumor therapy. ACS Nano 2022, 16, 8939-8953.
137. L. Dai, M. Yao, Z. Fu, X. Li, X. Zheng, S. Meng, Z. Yuan, K. Cai, H. Yang, Y. L. Zhao, Multifunctional metal-organic framework-based nanoreactor for starvation/oxidation improved indoleamine 2,3-dioxygenase-blockade tumor immunotherapy. Nat. Commun. 2022, 13, 2688.
136. Z. Wang, L. Gao, Y. Zheng, Y. Zhu, Y. Zhang, X. Zheng, C. Wang, Y. Li, Y. L. Zhao, C. Yang, Four-in-one stimulus-responsive long-lived luminescent systems based on pyrene-doped amorphous polymers. Angew. Chem. Int. Ed. 2022, 61, e202203254.
135. J. Guo, C. Yang, Y. L. Zhao, Long-lived organic room-temperature phosphorescence from amorphous polymer systems. Acc. Chem. Res. 2022, 55, 1160-1170.
134. Y. Chen, P. He, D. Jana, D. Wang, M. Wang, P. Yu, W. Zhu, Y. L. Zhao, Glutathione-depleting organic metal adjuvants for effective NIR-II photothermal immunotherapy. Adv. Mater. 2022, 34, 2201706.
133. Y. Zhang, X. Chen, J. Xu, Q. Zhang, L. Gao, Z. Wang, L. Qu, K. Wang, Y. Li, Z. Cai, Y. L. Zhao, C. Yang, Cross-linked polyphosphazene nanospheres boosting long-lived organic room temperature phosphorescence. J. Am. Chem. Soc. 2022, 144, 6107-6117.
132. F. Yang, R. Li, W. Wei, X. Ding, Z. Xu, P. Wang, G. Wang, Y. Xu, H. Fu, Y. L. Zhao, Water-soluble doubly-strapped isolated perylene diimide chromophore. Angew. Chem. Int. Ed. 2022, 61, e202202491.
131. Y. Li, M. Li, L. Liu, C. Xue, Y. Fei, X. Wang, Y. Zhang, K. Cai, Y. L. Zhao, Z. Luo, Cell-specific metabolic reprogramming of tumors for bioactivatable ferroptosis therapy. ACS Nano 2022, 16, 3965-3984.
130. G. Yang, D. Wang, S. Z. F. Phua, A. K. Bindra, C. Qian, R. Zhang, L. Cheng, G. Liu, H. Wu, Z. Liu, Y. L. Zhao, Albumin-based therapeutics capable of glutathione consumption and hydrogen peroxide generation for synergetic chemodynamic and chemotherapy of cancer. ACS Nano 2022, 16, 2319-2329.
129. H. Wang, Y. Yang, X. Yuan, W. L. Teo, Y. Wu, L. Tang, Y. L. Zhao, Structure-performance correlation guided applications of covalent organic frameworks. Mater. Today 2022, 53, 106-133.
128. C. Wang, Y. Zhang, Z. Wang, Y. Zheng, X. Zheng, L. Gao, Q. Zhou, J. Hao, B. Pi, Q. Li, C. Yang, Y. Li, K. Wang, Y. L. Zhao, Photo-induced dynamic room temperature phosphorescence based on triphenyl phosphonium containing polymers. Adv. Funct. Mater. 2022, 32, 2111941.
127. Y. Zhao, S. Song, X. Ren, J. Zhang, Q. Lin, Y. L. Zhao, Supramolecular adhesive hydrogels for tissue engineering applications. Chem. Rev. 2022, 122, 5604-5640.
126. Q. Zhang, M. He, X. Zhang, H. Yu, J. Liu, Y. Guo, J. Zhang, X. Ren, H. Wang, Y. L. Zhao, Tumor microenvironment activated chemodynamic-photodynamic therapy by multistage self-assembly engineered protein nanomedicine. Adv. Funct. Mater. 2022, 32, 2112251.
125. S. Dong, Y. Dong, B. Liu, J. Liu, S. Liu, Z. Zhao, W. Li, B. Tian, R. Zhao, F. He, S. Gai, Y. Xie, P. Yang, Y. L. Zhao, Guiding transition metal-doped hollow cerium tandem nanozymes with elaborately regulated multi-enzymatic activities for intensive chemodynamic therapy. Adv. Mater. 2022, 34, 2107054.
124. A. K. Bindra, S. Sreejith, R. Prasad, M. Gorain, R. Thomas, D. Jana, M. H. Nai, D. Wang, A. Tharayil, G. C. Kundu, R. Srivastava, S. Thomas, C. T. Lim, Y. L. Zhao, A plasmonic supramolecular nanohybrid as a contrast agent for site-selective computed tomography imaging of tumor. Adv. Funct. Mater. 2022, 32, 2110575.
123. J. Chen, L. Chen, Y. Wu, Y. Fang, F. Zeng, S. Wu, Y. L. Zhao, A H2O2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II fluorescent imaging. Nat. Commun. 2021, 12, 6870.
122. L. Gu, W. Ye, X. Liang, A. Lv, H. Ma, M. Singh, W. Jia, Z. Shen, Y. Guo, Y. Gao, H. Chen, D. Wang, Y. Wu, J. Liu, H. Wang, Y.-X. Zheng, Z. An, W. Huang, Y. L. Zhao, Circularly polarized organic room temperature phosphorescence from amorphous copolymers. J. Am. Chem. Soc. 2021, 143, 18527-18535.
121. W. Zhang, J. Liu, X. Li, Y. Zheng, L. Chen, D. Wang, M. F. Foda, Z. Ma, Y. L. Zhao, H. Han, Precise chemodynamic therapy of cancer by trifunctional bacterium-based nanozymes. ACS Nano 2021, 15, 19321-19333.
120. D. Wang, I. W. He, J. Liu, D. Jana, Y. Wu, X. Zhang, C. Qian, Y. Guo, X. Chen, A. K. Bindra, Y. L. Zhao, Missing-linker-assisted artesunate delivery by metal-organic frameworks for synergistic cancer treatment. Angew. Chem. Int. Ed. 2021, 60, 26254-26259.
119. Y. Li, G. V. Baryshnikov, C. Xu, H. Ågren, L. Zhu, T. Yi, Y. L. Zhao, H. Wu, Photoinduced radical emission in a coassembly system. Angew. Chem. Int. Ed. 2021, 60, 23842-23848.
118. D. Wang, Y. L. Zhao, Single-atom engineering of metal-organic frameworks toward healthcare. Chem 2021, 7, 2635-2671.
117. Y. Zhang, Y. Su, H. Wu, Z. Wang, C. Wang, Y. Zheng, X. Zheng, L. Gao, Q. Zhou, Y. Yang, X. Chen, C. Yang, Y. L. Zhao, Large-area, flexible, transparent, and long-lived polymer-based phosphorescence films. J. Am. Chem. Soc. 2021, 143, 13675-13685.
116. Z. Ma, Y. Zhang, X. Dai, W. Zhang, M. F. Foda, J. Zhang, Y. L. Zhao, H. Han, Selective thrombosis of tumor for enhanced hypoxia-activated prodrug therapy. Adv. Mater. 2021, 33, 2104504.
115. Z. Ma, M. F. Foda, H. Liang, Y. L. Zhao, H. Han, In situ nanozyme-amplified NIR-II phototheranostics for tumor-specific imaging and therapy. Adv. Funct. Mater. 2021, 31, 2103765.
114. B. Lu, Y. Bo, M. Yi, Z. Wang, J. Zhang, Z. Zhu, Y. L. Zhao, J. Zhang, Enhancing the solubility and transdermal delivery of drugs using ionic liquid-in-oil microemulsions. Adv. Funct. Mater. 2021, 31, 2102794.
113. Y. Wu, F. Zeng, Y. L. Zhao, S. Wu, Emerging contrast agents for multispectral optoacoustic imaging and their biomedical applications. Chem. Soc. Rev. 2021, 50, 7924-7940.
112. Q. Zhang, J. Zhang, J. Song, Y. Liu, X. Ren, Y. L. Zhao, Protein-based nanomedicine for therapeutic benefits of cancer. ACS Nano 2021, 15, 8001-8038.
111. D. Jana, D. Wang, A. K. Bindra, Y. Guo, J. Liu, Y. L. Zhao, Ultrasmall alloy nanozyme for ultrasound- and near-Infrared light-promoted tumor ablation. ACS Nano 2021, 15, 7774-7782.
110. B. Tian, S. Liu, L. Feng, S. Liu, S. Gai, Y. Dai, L. Xie, B. Liu, P. Yang, Y. L. Zhao, Renal-clearable nickel-doped carbon dots with boosted photothermal conversion efficiency for multimodal imaging-guided cancer therapy in the second near-infrared biowindow. Adv. Funct. Mater. 2021, 31, 2100549.
109. X. Zhang, X. Chen, Y. Guo, G. Gao, D. Wang, Y. Wu, J. Liu, G. Liang, Y. L. Zhao, F.-G. Wu, Dual gate-controlled therapeutics for overcoming bacterium-induced drug resistance and potentiating cancer immunotherapy. Angew. Chem. Int. Ed. 2021, 60, 14013-14021.
108. Y. Zhang, L. Gao, X. Zheng, Z. Wang, C. Yang, H. Tang, L. Qu, Y. Li, Y. L. Zhao, Ultraviolet irradiation-responsive dynamic ultralong organic phosphorescence in polymeric systems. Nat. Commun. 2021, 12, 2297.
107. J. Liang, A. Hao, P. Xing, Y. L. Zhao, Inverse evolution of helicity from molecular to macroscopic level based on N-terminal aromatic amino acids. ACS Nano 2021, 15, 5322-5332.
106. B. He, S. Jia, M. Zhao, Y. Wang, T. Chen, S. Zhao, Z. Li, Z. Lin, Y. L. Zhao, X. Liu, General and robust photothermal heating-enabled high-efficiency photoelectrochemical water splitting. Adv. Mater. 2021, 33, 2004406.
105. Z. Li, X. Liu, G. Wang, B. Li, H. Chen, H. Li, Y. L. Zhao, Photoresponsive supramolecular coordination polyelectrolyte as smart anticounterfeiting inks. Nat. Commun. 2021, 12, 1363.
104. W. L. Teo, W. Zhou, C. Qian, Y. L. Zhao, Industrializing metal-organic frameworks: scalable synthetic means and their transformation into functional materials. Mater. Today 2021, 47, 170-186.
103. H. Xiang, L. Zhao, L. Yu, H. Chen, C. Wei, Y. Chen, Y. L. Zhao, Self-assembled organic nanomedicine enables ultrastable photo-to-heat converting theranostics in the second near infrared biowindow. Nat. Commun. 2021, 12, 218.
102. D. Wang, H. Wu, C. Wang, L. Gu, H. Chen, D. Jana, L. Feng, J. Liu, X. Wang, P. Xu, Z. Guo, Q. Chen, Y. L. Zhao, Self-assembled single-site nanozyme for tumor-specific amplified cascade enzymatic therapy. Angew. Chem. Int. Ed. 2021, 60, 3001-3007.
101. L. Feng, B. Liu, R. Xie, D. Wang, C. Qian, W. Zhou, J. Liu, D. Jana, P. Yang, Y. L. Zhao, An ultrasmall SnFe2O4 nanozyme with endogenous oxygen generation and glutathione depletion for synergistic cancer therapy. Adv. Funct. Mater. 2021, 31, 2006216.
100. C. Qian, W. Zhou, J. Qiao, D. Wang, X. Li, W. L. Teo, X. Shi, H. Wu, J. Di, H. Wang, G. Liu, L. Gu, J. Liu, L. Feng, Y. Liu, S. Y. Quek, K. P. Loh, Y. L. Zhao, Linkage engineering by harnessing supramolecular interactions to fabricate 2D hydrazone-linked covalent organic framework platforms toward advanced catalysis. J. Am. Chem. Soc. 2020, 142, 18138-18149.
99. X. Liu, L. Xiao, J. Weng, Q. Xu, W. Li, C. Zhao, J. Xu, Y. L. Zhao, Regulating the reactivity of black phosphorus via protective chemistry. Sci. Adv. 2020, 6, eabb4359.
98. D. Wang, H. Wu, G. Yang, C. Qian, L. Gu, H. Wang, W. Zhou, J. Liu, Y. Wu, X. Zhang, Z. Guo, H. Chen, D. Jana, Y. L. Zhao, Metal-organic framework derived multicomponent nanoagent as a reactive oxygen species amplifier for enhanced photodynamic therapy. ACS Nano 2020, 14, 13500-13511.
97. Y. Liu, W. Zhou, W. L. Teo, K. Wang, L. Zhang, Y. Zeng, Y. L. Zhao, Covalent-organic-framework-based composite materials. Chem 2020, 6, 3172-3202.
96. X. Zhang, X. Chen, J. Song, J. Zhang, X. Ren, Y. L. Zhao, Size-transformable nanostructures: from design to biomedical applications. Adv. Mater. 2020, 32, 2003752.
95. X. Wang, M. Li, Y. Hou, Y. Li, X. Yao, C. Xue, Y. Fei, Y. Xiang, K. Cai, Y. L. Zhao, Z. Luo, Tumor-microenvironment-activated in situ self-assembly of sequentially responsive biopolymer for targeted photodynamic therapy. Adv. Funct. Mater. 2020, 30, 2000229.
94. D. Wang, D. Jana, Y. L. Zhao, Metal-organic framework derived nanozymes in biomedicine. Acc. Chem. Res. 2020, 53, 1389-1400.
93. X. Wei, D. Zheng, M. Zhao, H. Chen, X. Fan, B. Gao, L. Gu, Y. Guo, J. Qin, J. Wei, Y. L. Zhao, G. Zhang, Cross-linked polyphosphazene hollow nanosphere derived N/P doped porous carbon with single nonprecious metal atoms for oxygen reduction reaction. Angew. Chem. Int. Ed. 2020, 59, 14639-14646.
92. L. Feng, S. Gai, F. He, P. Yang, Y. L. Zhao, Multifunctional bismuth ferrite nanocatalysts with optical and magnetic functions for ultrasound enhanced tumor theranostics. ACS Nano 2020, 14, 7245-7258.
91. Y. Liu, S. Wang, X. Meng, Y. Ye, X. Song, Z. Liang, Y. L. Zhao, Molecular expansion for constructing porous organic polymers with high surface areas and well-defined nanopores. Angew. Chem. Int. Ed. 2020, 59, 19487-19493.
90. G. Zuo, Y. Wang, W. L. Teo, A. Xie, Y. Guo, Y. Dai, W. Zhou, D. Jana, Q. Xian, W. Dong, Y. L. Zhao, Ultrathin ZnIn2S4 nanosheets anchored on Ti3C2Tx MXene for photocatalytic H2 evolution. Angew. Chem. Int. Ed. 2020, 59, 11287-11292.
89. B. Han, Z. Duan, J. Xu, Y. Zhu, Q. Xu, H. Wang, H. Tai, J. Weng, Y. L. Zhao, The art of integrated functionalization: super stable black phosphorus achieved through metal-organic framework coating. Adv. Funct. Mater. 2020, 30, 2002232.
88. C. C. Xue, M. H. Li, Y. Zhao, J. Zhou, Y. Hu, K. Y. Cai, Y. L. Zhao, S. H. Yu, Z. Luo, Tumor microenvironment-activatable Fe-doxorubicin preloaded amorphous CaCO3 nanoformulation triggers ferroptosis in target tumor cells. Sci. Adv. 2020, 6, eaax1346.
87. H. Wang, C. Qian, J. Liu, Y. Zeng, D. Wang, W. Zhou, L. Gu, H. Wu, G. Liu, Y. L. Zhao, Integrating suitable linkage of covalent organic frameworks into covalently bridged inorganic/organic hybrids toward efficient photocatalysis. J. Am. Chem. Soc. 2020, 142, 4862-4871.
86. L. Gu, H. Wu, H. Ma, W. Ye, W. Jia, H. Wang, H. Chen, N. Zhang, D. Wang, C. Qian, Z. An, W. Huang, Y. L. Zhao, Color-tunable ultralong organic room temperature phosphorescence from a multicomponent copolymer. Nat. Commun. 2020, 11, 944.
85. T. Zhang, X. Ma, H. Wu, L. Zhu, Y. L. Zhao, H. Tian, Molecular engineering for metal-free amorphous room-temperature phosphorescent materials. Angew. Chem. Int. Ed. 2020, 59, 11206-11216.
84. Z. Wang, Y. Zhang, C. Wang, X. Zheng, Y. Zheng, L. Gao, C. Yang, Y. Li, L. Qu, Y. L. Zhao, Color-tunable polymeric long-persistent luminescence based on polyphosphazenes. Adv. Mater. 2020, 32, 1907355.
83. D. Wang, H. Wu, S. Z. F. Phua, G. Yang, W. Q. Lim, L. Gu, C. Qian, H. Wang, Z. Guo, H. Chen, Y. L. Zhao, Self-assembled single-atom nanozyme form enhanced photodynamic therapy treatment of tumor. Nat. Commun. 2020, 11, 357.
82. L. Zhao, J. Li, Y. Su, L. Yang, L. Chen, L. Qiang, Y. Wang, H. Xiang, H. P. Tham, J. Peng, Y. L. Zhao, MTH1 inhibitor amplifies the lethality of reactive oxygen species to tumor in photodynamic therapy. Sci. Adv. 2020, 6, eaaz0575.
81. Y. Su, Y. Zhang, Z. Wang, W. Gao, P. Jia, D. Zhang, C. Yang, Y. Li, Y. L. Zhao, Excitation-dependent long-life luminescent polymeric systems under ambient conditions. Angew. Chem. Int. Ed. 2020, 59, 9967-9971.
80. L. Sun, Y. Zhuang, Y. Yuan, W. Zhan, X. J. Wang, X. Han, Y. L. Zhao, Nitrogen-doped carbon-coated CuO-In2O3 p-n heterojunction for remarkable photocatalytic hydrogen evolution. Adv. Energy Mater. 2019, 9, 1902839.
79. Y. Zhai, G. Liu, F. Jin, Y. Zhang, X. Gong, Z. Miao, J. Li, M. Zhang, Y. Cui, L. Zhang, Y. Liu, H. Zhang, Y. L. Zhao, Y. Zeng, Construction of covalent-organic frameworks (COFs) from amorphous covalent organic polymers via linkage replacement. Angew. Chem. Int. Ed. 2019, 58, 17679-17683.
78. W. Cheng, X. Zeng, H. Chen, Z. Li, W. Zeng, L. Mei, Y. L. Zhao, Versatile polydopamine platforms: synthesis and promising applications for surface modification and advanced nanomedicine. ACS Nano 2019, 13, 8537-8565.
77. Y. Wang, S. Z. F. Phua, G. Dong, X. Liu, B. He, Q. Zhai, Y. Li, C. Zheng, H. Quan, Z. Li, Y. L. Zhao, Structure tuning of polymeric carbon nitride for solar energy conversion: from nano to molecular scale. Chem 2019, 5, 2775-2813.
76. H. Wu, Z. Chen, W. Chi, B. A. Kaur, L. Gu, C. Qian, B. Wu, B. Yue, G. Liu, G. Yang, L. Zhu, Y. L. Zhao, Structural engineering of luminogens with high emission efficiency both in solution and the solid state. Angew. Chem. Int. Ed. 2019, 58, 11419-11423.
75. P. Xing, Y. Li, S. Xue, S. Z. F. Phua, C. Ding, H. Chen, Y. L. Zhao, Occurrence of chiral nanostructures induced by multiple hydrogen bonds. J. Am. Chem. Soc. 2019, 141, 9946-9954.
74. G. Liu, C. Zhou, W. L. Teo, C. Qian, Y. L. Zhao, Self-sorting double-network hydrogels with tunable supramolecular handedness and mechanical property. Angew. Chem. Int. Ed. 2019, 58, 9366-9372.
73. H. Wu, Y. L. Zhao, Colour-tunable ultralong emission. Nat. Photonics 2019, 13, 373-375.
72. D. Wang, H. Wu, W. Q. Lim, S. Z. F. Phua, P. Xu, Q. Chen, Z. Guo, Y. L. Zhao, A mesoporous nanoenzyme derived from metal-organic frameworks with endogenous oxygen generation to alleviate tumor hypoxia for significantly enhanced photodynamic therapy. Adv. Mater. 2019, 31, 1901893.
71. L. Sun, R. Li, W. Zhan, Y. Yuan, X. Wang, X. Han, Y. L. Zhao, Double-shelled hollow rods assembled from nitrogen/sulfur-codoped carbon coated indium oxide nanoparticles as excellent photocatalysts. Nat. Commun. 2019, 10, 2270.
70. G. Yang, S. Z. F. Phua, W. Q. Lim, R. Zhang, L. Feng, G. Liu, H. Wu, A. K. Bindra, D. Jana, Z. Liu, Y. L. Zhao, A hypoxia-responsive albumin-based nanosystem for deep tumor penetration and excellent therapeutic efficacy. Adv. Mater. 2019, 31, 1901513.
69. H. Chen, X. Zeng, H. P. Tham, S. Z. F. Phua, W. Cheng, W. Zeng, H. Shi, L. Mei, Y. L. Zhao, NIR-light-activated combination therapy with a precise ratio of photosensitizer and prodrug using a host-guest strategy. Angew. Chem. Int. Ed. 2019, 58, 7641-7646.
68. S. Z. F. Phua, G. Yang, W. Q. Lim, A. Verma, H. Chen, T. Thanabalu, Y. L. Zhao, Catalase integrated hyaluronic acid as nanocarriers for enhanced photodynamic therapy in solid tumor. ACS Nano 2019, 13, 4742-4751.
67. Z. Miao, G. Liu, Y. Cui, Z. Liu, J. Li, F. Han, Y. Liu, X. Sun, X. Gong, Y. Zhai, Y. L. Zhao, Y. Zeng, A novel strategy for construction of covalent organic frameworks from nonporous covalent organic polymers. Angew. Chem. Int. Ed. 2019, 58, 4906-4910.
66. G. Yang, S. Z. F. Phua, A. K. Bindra, Y. L. Zhao, Degradability and clearance of inorganic nanoparticles for biomedical applications. Adv. Mater. 2019, 31, 1805730.
65. H. Wu, W. Chi, Z. Chen, G. Liu, L. Gu, A. K. Bindra, G. Yang, X. Liu, Y. L. Zhao, Achieving amorphous ultralong room temperature phosphorescence by coassembling planar small organic molecules with polyvinyl alcohol. Adv. Funct. Mater. 2019, 29, 1807243.
64. G. Liu, J. Sheng, W. L. Teo, G. Yang, H. Wu, Y. Li, Y. L. Zhao, Control on dimensions and supramolecular chirality of self-assemblies through light and metal ions. J. Am. Chem. Soc. 2018, 140, 16275-16283.
63. H. P. Tham, K. Xu, W. Q. Lim, H. Chen, M. Zheng, T. G. S. Thng, S. S. Venkatraman, C. Xu, Y. L. Zhao, Microneedle-assisted topical delivery of photodynamically active mesoporous formulation for combination therapy of deep-seated melanoma. ACS Nano 2018, 12, 11936-11948.
62. L. Zhao, W. Yuan, J. Li, L. Yang, Y. Su, J. Peng, R. Chen, H. P. Tham, H. Chen, W. Q. Lim, H. Xiang, P. Xing, F. Li, Y. L. Zhao, Independent of EPR effect: a smart delivery nanosystem for tracking and treatment of nonvascularized intra-abdominal metastases. Adv. Funct. Mater. 2018, 28, 1806162.
61. P. Xing, S. Z. F. Phua, X. Wei, Y. L. Zhao, Programmable multicomponent self-assembly based on aromatic amino acids. Adv. Mater. 2018, 30, 1805175.
60. P. Xing, Y. L. Zhao, Controlling supramolecular chirality in multicomponent self-assembled systems. Acc. Chem. Res. 2018, 51, 2324-2334.
59. P. Xing, C. Yang, Y. Wang, S. Z. F. Phua, Y. L. Zhao, Solvent-controlled assembly of aromatic glutamic dendrimers for efficient luminescent color conversion. Adv. Funct. Mater. 2018, 28, 1802859.
58. Z. Liu, H. Zhang, Y. L. Zhao, Pillararene-based self-assembled amphiphiles. Chem. Soc. Rev. 2018, 47, 5491-5528.
57. G. Liu, J. Sheng, H. Wu, C. Yang, G. Yang, Y. Li, R. Ganguly, L. Zhu, Y. L. Zhao, Controlling supramolecular chirality of two-component hydrogels by J- and H-aggregation of building blocks. J. Am. Chem. Soc. 2018, 140, 6467-6473.
56. Y. Su, S. Z. F. Phua, Y. Li, X. Zhou, D. Jana, G. Liu, W. Q. Lim, W. K. Ong, C. Yang, Y. L. Zhao, Ultralong room temperature phosphorescence from amorphous organic materials toward confidential information encryption and decryption. Sci. Adv. 2018, 4, eaas9732.
55. P. Xing, Y. Li, Y. Wang, P. Z. Li, H. Chen, S. Z. F. Phua, Y. L. Zhao, Water binding mediated gelation/crystallization and thermosensitive superchirality. Angew. Chem. Int. Ed. 2018, 57, 7774-7779.
54. X. Zhang, Z. Luo, P. Yu, Y. Cai, Y. Du, D. Wu, S. Gao, C. Tan, Z. Li, M. Ren, T. Osipowicz, S. Chen, Z. Jiang, J. Li, Y. Huang, J. Yang, Y. Chen, C. Y. Ang, Y. L. Zhao, P. Wang, L. Song, X. Wu, Z. Liu, A. Borgna, H. Zhang, Lithiation-induced amorphization of Pd3P2S8 for highly efficient hydrogen evolution. Nat. Catal. 2018, 1, 460-468.
53. Y. Wang, X. Liu, J. Liu, B. Han, X. Hu, F. Yang, Z. Xu, Y. Li, S. Jia, Z. Li, Y. L. Zhao, Carbon quantum dot implanted graphite carbon nitride nanotubes: excellent charge separation and enhanced photocatalytic hydrogen evolution. Angew. Chem. Int. Ed. 2018, 57, 5765-5771.
52. P. Xing, H. Chen, H. Xiang, Y. L. Zhao, Selective co-assembly of aromatic amino acids to fabricate hydrogels with light irradiation induced emission for fluorescent imprint. Adv. Mater. 2018, 30, 1705633.
51. G. Liu, X. Li, J. Sheng, P. Z. Li, W. K. Ong, S. Z. F. Phua, H. Agren, L. Zhu, Y. L. Zhao, Helicity inversion of supramolecular hydrogels induced by achiral substituents. ACS Nano 2017, 11, 11880-11889.
50. C. Tan, L. Zhao, P. Yu, Y. Huang, B. Chen, Z. Lai, X. Qi, M. H. Goh, X. Zhang, S. Han, X. J. Wu, Z. Liu, Y. L. Zhao, H. Zhang, Preparation of ultrathin two-dimensional TixTa1-xSyOz nanosheets as highly efficient photothermal agents. Angew. Chem. Int. Ed. 2017, 56, 7842-7846.
49. J. Liang, Z. Liang, R. Zou, Y. L. Zhao, Heterogeneous catalysis in zeolites, mesoporous silica, and metal-organic frameworks. Adv. Mater. 2017, 29, 1701139.
48. P. Xing, P. Li, H. Chen, A. Hao, Y. L. Zhao, Understanding pathway complexity of organic micro/nanofiber growth in hydrogen bonded co-assembly of aromatic amino acids. ACS Nano 2017, 11, 4206-4216.
47. X. Yao, Y. L. Zhao, Three-dimensional porous graphene networks and hybrids for lithium-ion battery and supercapacitors. Chem 2017, 2, 171-200.
46. P. Xing, Y. L. Zhao, Multifunctional nanoparticles self-assembled from small organic building blocks for biomedicine. Adv. Mater. 2016, 28, 7304-7339.
45. T. Feng, X. Ai, G. An, P. Yang, Y. L. Zhao, Charge-convertible carbon dots for imaging-guided drug delivery with enhanced in vivo cancer therapeutic efficiency. ACS Nano 2016, 10, 4410-4420.
44. P. Z. Li, X. J. Wang, J. Liu, J. S. Lim, R. Zou, Y. L. Zhao, A trazole-containing metal-organic framework as a highly effective and substrate size-dependent catalyst for CO2 conversion. J. Am. Chem. Soc. 2016, 138, 2142-2145.
43. P. Xing, H. Chen, L. Bai, A. Hao, Y. L. Zhao, Superstructure formation and topological evolution achieved by self-organization of a highly adaptive dynamer. ACS Nano 2016, 10, 2716-2727.
42. L. Zhao, W. Yuan, C. Y. Ang, Q. Qu, Y. Dai, Y. Gao, Z. Luo, J. G. Wang, H. Chen, M. Li, F. Li, Y. L. Zhao, Silica-polymer hybrid with self-assembled PEG corona excreted rapidly via a hepatobiliary route. Adv. Funct. Mater. 2016, 26, 3036-3047.
41. Y. Zeng, R. Zou, Y. L. Zhao, Covalent organic frameworks for CO2 capture. Adv. Mater. 2016, 28, 2855-2873.
40. L. Bai, Y. L. Zhao, Interlocked moelcules - aqueous assembly. Nat. Chem. 2015, 7, 944-945.
39. K. T. Nguyen, Y. L. Zhao, Engineering hybrid nanoparticles for on-demand diagnostics and therapeutics. Acc. Chem. Res. 2015, 48, 3016-3025.
38. P. Z. Li, X. J. Wang, S. Y. Tan, C. Y. Ang, H. Chen, J. Liu, R. Zou, Y. L. Zhao, Clicked isoreticular metal-organic frameworks and their high performance on selective capture and separation of large organic molecules. Angew. Chem. Int. Ed. 2015, 54, 12748-12752.
37. M. Li, C. Teh, C. Y. Ang, S. Y. Tan, Z. Luo, Q. Qu, Y. Zhang, V. Korzh, Y. L. Zhao, Near-infrared light-absorptive stealth liposomes for localized photothermal ablation of tumors combined with chemotherapy. Adv. Funct. Mater. 2015, 25, 5602-5610.
36. P. Borah, S. Sreejith, P. Anees, N. V. Menon, Y. Kang, A. Ajayaghosh, Y. L. Zhao, Near-IR squaraine dye-loaded gated periodic mesoporous organosilica for photo-oxidation of phenol in continuous-flow device. Sci. Adv. 2015, 1, e1500390.
35. S. Sreejith, J. Joseph, M. Lin, N. V. Menon, P. Borah, H. J. Ng, Y. X. Loong, Y. Kang, S. W. K. Yu, Y. L. Zhao, Near-infrared squaraine dye encapsulated micelles for in vivo fluorescence and photoacoustic bimodal imaging. ACS Nano 2015, 9, 5695-5704.
34. A. K. Mandal, S. Sreejith, T. He, S. K. Maji, X. J. Wang, S. L. Ong, J. Joseph, H. Sun, Y. L. Zhao, Three photon-excited luminescence from unsymmetrical cyanostilbene aggregates: morphology tuning and targeted bioimaging. ACS Nano 2015, 9, 4796-4805.
33. X. Ma, Y. L. Zhao, Biomedical applications of supramolecular systems based on host-guest interactions. Chem. Rev. 2015, 115, 7794-7839.
32. Y. Zeng, R. Zou, Z. Luo, H. Zhang, X. Yao, R. Zou, Y. L. Zhao, Covalent organic frameworks formed with two types of covalent bonds based on orthogonal reactions. J. Am. Chem. Soc. 2015, 137, 1020-1023.
31. Y. Zhao, Z. Luo, M. Li, Q. Qu, X. Ma, S. H. Yu, Y. L. Zhao, A preloaded amorphous calcium carbonate-doxorubicin@silica nanoreactor for pH-responsive delivery of anticancer drug. Angew. Chem. Int. Ed. 2015, 54, 919-922.
30. S. K. Maji, S. Sreejith, J. Joseph, M. Lin, T. He, Y. Tong, H. Sun, S. W. K. Yu, Y. L. Zhao, Upconversion nanoparticles as a contrast agent for photoacoustic imaging in live mice. Adv. Mater. 2014, 26, 5633-5638.
29. A. Jana, K. T. Nguyen, X. Li, P. Zhu, N. S. Tan, H. Agren, Y. L. Zhao, Perylene-derived single-component organic nanoparticles with tunable emission: efficient anticancer drug carriers with real-time monitoring of drug release. ACS Nano 2014, 8, 5939-5952.
28. H. Shi, X. Ma, Q. Zhao, B. Liu, Q. Qu, Z. An, Y. L. Zhao, W. Huang, Ultrasmall phosphorescent polymer dots for ratiometric oxygen sensing and photodynamic cancer therapy. Adv. Funct. Mater. 2014, 24, 4823-4830.
27. Q. Zhang, X. Wang, P. Z. Li, K. T. Nguyen, X. J. Wang, Z. Luo, H. Zhang, N. S. Tan, Y. L. Zhao, Biocompatible, uniform, and redispersible mesoporous silica nanoparticles for cancer-targeting drug delivery in vivo. Adv. Funct. Mater. 2014, 24, 2450-2461.
26. Z. Luo, X. Ding, Y. Hu, S. Wu, Y. Xiang, Y. Zeng, B. Zhang, H. Yan, H. Zhang, L. Zhu, J. Liu, J. Li, K. Cai, Y. L. Zhao, Engineering a hollow nanocontainer platform with multifunctional molecular machines for tumor-targeted therapy in vitro and in vivo. ACS Nano 2013, 7, 10271-10284.
25. H. Zhang, X. Ma, K. T. Nguyen, Y. L. Zhao, Biocompatible pillararene-assembly-based carriers for dual bioimaging. ACS Nano 2013, 7, 7853-7863.
24. L. Zhu, X. Li, S. Wu, K. T. Nguyen, H. Yan, H. Agren, Y. L. Zhao, Chirality control in in-situ preparation of gold nanoparticle superstructures directed by a coordinatable organogelator. J. Am. Chem. Soc. 2013, 135, 9174-9180.
23. L. Zhu, X. Li, Q. Zhang, X. Ma, M. Li, H. Zhang, Z. Luo, H. Agren, Y. L. Zhao, Unimolecular photoconversion of multicolor luminescence on hierarchical self-assemblies. J. Am. Chem. Soc. 2013, 135, 5175-5182.
22. H. Li, C. Cheng, P. R. McGonigal, A. C. Fahrenbach, M. Frasconi, W. G. Liu, Z. Zhu, Y. L. Zhao, C. Ke, J. Lei, R. M. Young, S. M. Dyar, D. T. Co, Y. W. Yang, Y. Y. Botros, W. A. Goddard, M. R. Wasielewski, R. D. Astumian, J. F. Stoddart, Relative unidirectional translation in an artificial molecular assembly fueled by light. J. Am. Chem. Soc. 2013, 135, 18609-18620.
21. H. Li, Z. Zhu, A. C. Fahrenbach, B. M. Savoie, C. Ke, J. C. Barnes, J. Lei, Y. L. Zhao, L. M. Lilley, T. J. Marks, M. A. Ratner, J. F. Stoddart, Mechanical bond-induced radical stabilization. J. Am. Chem. Soc. 2013, 135, 456-467.
20. S. Sreejith, X. Ma, Y. L. Zhao, Graphene oxide wrapping on squaraine-loaded mesoporous silica nanoparticles for bioimaging. J. Am. Chem. Soc. 2012, 134, 17346-17349.
19. Q. Zhang, F. Liu, K. T. Nguyen, X. Ma, X. Wang, B. Xing, Y. L. Zhao, Multifunctional mesoporous silica nanoparticles for cancer-targeted and controlled drug delivery. Adv. Funct. Mater. 2012, 22, 5144-5156.
18. H. Yan, C. Teh, S. Sreejith, L. Zhu, A. Kwok, W. Fang, X. Ma, K. T. Nguyen, V. Korzh, Y. L. Zhao, Functional mesoporous silica nanoparticles for photothermal-controlled drug delivery in vivo. Angew. Chem. Int. Ed. 2012, 51, 8373-8377.
17. P. Borah, X. Ma, K. T. Nguyen, Y. L. Zhao, A vanadyl complex grafted to periodic mesoporous organosilica: a green catalyst for selective hydroxylation of benzene to phenol. Angew. Chem. Int. Ed. 2012, 51, 7756-7761.
16. L. Zhu, C. Y. Ang, X. Li, K. T. Nguyen, S. Y. Tan, H. Agren, Y. L. Zhao, Luminescent color conversion on cyanostilbene functionalized quantum dots via in-situ photo-tuning. Adv. Mater. 2012, 24, 4020-4024.
15. C. Wang, Z. Li, D. Cao, Y. L. Zhao, J. W. Gaines, O. A. Bozdemir, M. W. Ambrogio, M. Frasconi, Y. Y. Botros, J. I. Zink, J. F. Stoddart, Stimulated release of size-selected cargos in succession from mesoporous silica nanoparticles. Angew. Chem. Int. Ed. 2012, 51, 5460-5465.
14. M. W. Ambrogio, C. R. Thomas, Y. L. Zhao, J. I. Zink, J. F. Stoddart, Mechanized silica nanoparticles: a new frontier in theranostic nanomedicine. Acc. Chem. Res. 2011, 44, 903-913.
13. H. Li, A. C. Fahrenbach, A. Coskun, Z. Zhu, G. Barin, Y. L. Zhao, Y. Y. Botros, J. P. Sauvage, J. F. Stoddart, A light-stimulated moelcular switch driven by radical-radical interactions in water. Angew. Chem. Int. Ed. 2011, 50, 6782-6788.
12. Y. L. Zhao, Z. Li, S. Kabehie, Y. Y. Botros, J. F. Stoddart, J. I. Zink, pH-Operated nanopistons on the surfaces of mesoporous silica nanoparticles. J. Am. Chem. Soc. 2010, 132, 13016-13025.
11. H. Meng, M. Xue, T. Xia, Y. L. Zhao, S. Kabehie, F. Tamanoi, J. F. Stoddart, J. I. Zink, A. E. Nel, Autonomous in vitro anticancer drug release from mesoporous silica nanoparticles derivatized with pH-sensitive supramolecular nanovalves. J. Am. Chem. Soc. 2010, 132, 12690-12697.
10. Y. L. Zhao, J. F. Stoddart, Noncovalent functionalization of single-walled carbon nanotubes. Acc. Chem. Res. 2009, 42, 1161-1171.
9. Q. Li, W. Zhang, Q. S. Mijanic, C. H. Sue, Y. L. Zhao, L. Liu, C. Knobler, J. F. Stoddart, O. M. Yaghi, Docking in metal-organic frameworks. Science 2009, 325, 855-859.
8. D. Ferris, Y. L. Zhao, N. M. Khashab, H. A. Khatib, J. F. Stoddart, J. I. Zink, Light-operated mechanized nanoparticles. J. Am. Chem. Soc. 2009, 131, 1686-1688.
7. Y. L. Zhao, L. Hu, G. Gruner, J. F. Stoddart, A tunable photosensor. J. Am. Chem. Soc. 2008, 130, 16996-17003.
6. Y. L. Zhao, W. R. Dichtel, A. Trabolsi, S. Saha, I. Aprahamian, J. F. Stoddart, A redox-switchable alpha-cyclodextrin-based [2]rotaxane. J. Am. Chem. Soc. 2008, 130, 11294-11296.
5. Y. L. Zhao, I. Aprahamian, A. Trabolsi, N. Erina, J. F. Stoddart, Organogel formation by a cholesterol-stoppered bistable [2]rotaxane and its dumbbell precusor. J. Am. Chem. Soc. 2008, 130, 6348-6350.
4. Y. L. Zhao, L. Hu, J. F. Stoddart, G. Gruner, Pyrenecyclodextrin-decorated single-walled carbon nanotube field-effect transistor as chemical sensor. Adv. Mater. 2008, 20, 1910-1915.
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