Welcome to The Zhao Group
Selected Publications

150. L.-B. Xing, K. Cheng, H. Li, K. Niu, T.-X. Luan, S. Kong, W. W. Yu, P.-Z. Li, Y. L. Zhao, Integrating two photochromics into one three-dimensional covalent organic framework for synergistically enhancing multiple photocatalytic cxidations. Angew. Chem. Int. Ed. 2025, accepted

149. S. Tang, S. Jiang, K. Wang, Y. Zhang, L. Yi, J. Hou, L. Qu, Y. L. Zhao, C. Yang,
Cycloolefin copolymers with a multiply rigid structure for protecting triplet exciton from thermo- and moisture-quenching. Adv. Mater. 2025, accepted.

148. H. Zhao, S. Jin, Y. Liu, Q. Wang, B. S. N. Tan, S. Wang, W.-K. Han, X. Niu, Y. L. Zhao,
A second near-infrared window-responsive metal-organic framework-based photosensitizer for tumor immunotherapy via synergistic ferroptosis and STING activation. J. Am. Chem. Soc. 2025, accepted.

147. M. Ma, J. Wang, K. Guo, W. Zhong, Y. Cheng, L. Lin, Y. L. Zhao,
A self-reinforced “microglia energy modulator” for synergistic amyloid-β clearance in Alzheimer’s disease model. Angew. Chem. Int. Ed. 2025, accepted.

146. C. Wang, W. Zhong, X. Sun, J. Guo, Y. Chen, Y. Zhao, J. Han, Y. L. Zhao,
NIR-activable charge transfer agents for synergistic photoimmunotherapy. Angew. Chem. Int. Ed. 2025, 64, e202416828.

145. Y. Liu, H. Zhao, R. Niu, B. Zhang, B. T. G. Lim, S. Song, Y. Wang, H. Zhang, Y. L. Zhao,
Single-site nanozyme with exposed unsaturated Cu-O2 sites for tumor therapy by coordinating innate immunity and vasculature normalization. Chem 2025, accepted.

144. X. Chen, X. Zhang, Y. L. Zhao,
Metal–organic framework-based hybrids with photon upconversion. Chem. Soc. Rev. 2025, 54, 152-177.

143. X. Chen, X. Zhang, Y. Liu, Y. Chen, Y. L. Zhao,
Upconversion nanoparticle-anchored metal–organic framework nanostructures for remote-controlled cancer optogenetic therapy. J. Am. Chem. Soc. 2024, 146, 34475-34490.

142. K. Fu, Y. L. Zhao, G. Liu,
Pathway-directed recyclable chirality inversion of coordinated supramolecular polymers. Nat. Commun. 2024, 15, 9571.

141. Y. Liu, H. Zhao, S. Wang, R. Niu, S. Bi, W.-K. Han, Y. Wang, S. Song, H. Zhang, Y. L. Zhao,
A Wurster-type covalent organic framework with internal electron transfer-enhanced catalytic capacity for tumor therapy. J. Am. Chem. Soc. 2024, 146, 27345-27361.

140. Y. Cheng, W. Zhong, Y. Chen, B. S. N. Tan, Y. Zhao, J. Guo, M. Ma, Y. L. Zhao,
Bimetal-biligand frameworks for spatiotemporal nitric oxide-enhanced sono-immunotherapy. Adv. Mater. 2024, 36, 2408242.

139. Q. Huang, C. Ding, W. Wang, L. Yang, Y. Wu, W. Zeng, Z. Li, Z. Shi, L. Mei, X. Zeng, Y. L. Zhao, H. Chen,
An “AND” logic gate based supramolecular therapeutic nanoplatform for combatting drug-resistant non-small cell lung cancer. Sci. Adv. 2024, 10, adp9071.

138. Y. Chen, B. S. N. Tan, Y. Cheng, Y. L. Zhao,
Artificial polymerizations in living organisms for biomedical applications. Angew. Chem. Int. Ed. 2024, 63, e202410579.

137. C. Zhang, Y. Wu, F. Zeng, Y. Wen, J. Chen, G. Deng, L. Zhang, S. Zhao, S. Wu, Y. L. Zhao,
Structurally modulated formation of cyanine J-aggregates with sharp and tunable spectra for multiplexed optoacoustic and fluorescence bioimaging. Angew. Chem. Int. Ed. 2024, 63, e202406694.

136. W. Fang, J. Zhang, M. Guo, Y. L. Zhao, A. C.-H. Sue,
Triphenylamine[3]arenes: Streamlining synthesis of a versatile macrocyclic platform for supramolecular architectures and functionalities. Angew. Chem. Int. Ed. 2024, 63, e202409120.

135. T. He, I. K. W. On, S. Bi, Z. Huang, J. Guo, Z. Wang, Y. L. Zhao,
Crystalline olefin-linked chiral covalent organic frameworks as a platform for asymmetric catalysis. Angew. Chem. Int. Ed. 2024, 63, e202405769.

134. W. Zhong, W. Yuan, Y. Chen, Z. Ma, M. Ma, B. S. N. Tan, J. Yang, Y. L. Zhao,
Activable nano-immunomodulator assembled from π-extended naphthalenediimide for precision photothermal immunotherapy. Angew. Chem. Int. Ed. 2024, 63, e202401250.

133. B. He, Y. Cao, K. Lin, Y. Wang, Z. Li, Y. Yang, Y. L. Zhao, X. Liu,
Strong interactions between Au nanoparticles and BiVO4 photoanode boosts hole extraction for photoelectrochemical water splitting. Angew. Chem. Int. Ed. 2024, 63, e202402435.

132. Z. Ma, P. Zeng, T. Zhai, Y. L. Zhao, H. Liang,
In situ mitochondrial biomineralization for drug-free cancer therapy. Adv. Mater. 2024, 36, 2310218.

131. J.-R. Wang, K. Song, T.-X. Luan, K. Cheng, Q. Wang, Y. Wang, W. W. Yu, P.-Z. Li, Y. L. Zhao,
Robust links in photoactive covalent organic frameworks enable effective photocatalytic reactions under harsh conditions. Nat. Commun. 2024, 15, 1267.

130. X. Wu, Y. Li, M. Wen, Y. Xie, K. Zeng, Y.-N. Liu, W. Chen, Y. L. Zhao,
Nanocatalysts for modulating antitumor immunity: fabrications, mechanisms and applications. Chem. Soc. Rev. 2024, 53, 2643-2692.

129. Y. Liu, R. Niu, H. Zhao, Y. Wang, S. Song, H. Zhang, Y. L. Zhao,
Single-site nanozymes with a highly conjugated coordination structure for antitumor immunotherapy via cuproptosis and cascade-enhanced T lymphocyte activity. J. Am. Chem. Soc. 2024, 146, 3675-3688.

128. Y. Liu, H. Zhao, Y. L. Zhao,
Designing efficient single metal atom biocatalysts at the atomic structure level. Angew. Chem. Int. Ed. 2024, 63, e202315933.

127. L. Ma, Y. Cheng, X. Feng, X. Zhang, J. Lei, H. Wang, Y. Xu, B. Tong, D. Zhu, D. Wu, X. Zhou, H. Liang, K. Zhao, K. Wang, L. Tan, Y. L. Zhao, C. Yang,
A Janus-ROS healing system promoting infectious bone regeneration via sono-epigenetic modulation. Adv. Mater. 2024, 36, 2307846.

126. Y. Xiong, Q. Feng, L. Lu, X. Qiu, S. Knoedler, A. C. Panayi, D. Jiang, Y. Rinkevich, Z. Lin, B. Mi, G. Liu, Y. L. Zhao, Metal–organic frameworks and their composites for chronic wound healing: from bench to bedside. Adv. Mater. 2024, 36, 2302587.

125. D. Jana, B. He, Y. Chen, J. Liu, Y. L. Zhao, A defect-engineered nanozyme for targeted NIR-II photothermal immunotherapy of cancer. Adv. Mater. 2024, 36, 2206401.

124. W. Yuan, L. Chen, C. Yuan, Z. Zhang, X. Chen, X. Zhang, J. Guo, C. Qian, Z. Zhao, Y. L. Zhao, Cooperative supramolecular polymerization of styrylpyrenes for color-dependent circularly polarized luminescence and photocycloaddition. Nat. Commun. 2023, 14, 8022.

123. L. Gao, J. Huang, L. Qu, X. Chen, Y. Zhu, C. Li, Q. Tian, Y. L. Zhao, C. Yang,
Stepwise taming of triplet excitons via multiple confinements in intrinsic polymers for long-lived room-temperature phosphorescence. Nat. Commun. 2023, 14, 7252.

122. L. Yang, D. Zhang, W. Li, H. Lin, C. Ding, Q. Liu, L. Wang, Z. Li, L. Mei, H. Chen, Y. L. Zhao, X. Zeng,
Biofilm microenvironment triggered self-enhancing photodynamic immunomodulatory microneedle for diabetic wound therapy. Nat. Commun. 2023, 14, 7658.

121. Z. Shi, M. Luo, Q. Huang, C. Ding, W. Wang, Y. Wu, J. Luo, C. Lin, T. Chen, X. Zeng, L. Mei, Y. L. Zhao, H. Chen,
NIR-dye bridged human serum albumin reassemblies for effective photothermal therapy of tumor. Nat. Commun. 2023, 14, 6567.

120. Y. Dong, S. Dong, C. Yu, J. Liu, S. Gai, Y. Xie, Z. Zhao, X. Qin, L. Feng, P. Yang, Y. L. Zhao,
Mitochondria-targeting Cu3VS4 nanostructure with high copper ionic mobility for photothermoelectric therapy. Sci. Adv. 2023, 9, adi9980.

119. S. Wang, T. Wu, S. Wu, J. Guo, T. He, Y. Wu, W. Yuan, Z. Zhang, Y. Hua, Y. L. Zhao,
Cobaloxime-integrated covalent organic frameworks for photocatalytic hydrogen evolution coupled with alcohol oxidation. Angew. Chem. Int. Ed. 2023, 62, e202311082.

118. Y. Chen, M. Zuo, Y. Chen, P. Yu, X. Chen, X. Zhang, W. Yuan, Y. Wu, W. Zhu, Y. L. Zhao,
Nanocompartment-confined polymerization in living systems. Nat. Commun. 2023, 14, 5229.

117. C. Qin, X. Wu, L. Tang, X. Chen, M. Li, Y. Mou, B. Su, S. Wang, C. Feng, J. Liu, X. Yuan, Y. L. Zhao, H. Wang,
Dual donor-acceptor covalent organic frameworks for hydrogen peroxide photosynthesis. Nat. Commun. 2023, 14, 5238.

116. B. Luo, W. Wang, Y. Zhao, Y. L. Zhao,
Hot-electron dynamics mediated medical diagnosis and therapy. Chem. Rev. 2023, 123, 10808-10833.

115. T. He, R. Liu, S. Wang, I. K. W. On, Y. Wu, Y. Xing, W. Yuan, J. Guo, Y. L. Zhao,
Bottom-up design of photoactive chiral covalent organic frameworks for visible light-driven asymmetric catalysis. J. Am. Chem. Soc. 2023, 145, 18015-18021.

114. Y. Wu, L. Sun, X. Chen, J. Liu, J. Ouyang, X. Zhang, Y. Guo, Y. Chen, W. Yuan, D. Wang, T. He, F. Zeng, H. Chen, S. Wu, Y. L. Zhao,
Cucurbit[8]uril-based water-dispersible assemblies with enhanced optoacoustic performance for multispectral optoacoustic imaging. Nat. Commun. 2023, 14, 3918.

113. D. Wang, J. Liu, C. Wang, W. Zhang, G. Yang, Y. Chen, X. Zhang, Y. Wu, L. Gu, H. Chen, W. Yuan, X. Chen, G. Liu, B. Gao, Q. Chen, Y. L. Zhao,
Microbial synthesis of Prussian blue for potentiating checkpoint blockade immunotherapy. Nat. Commun. 2023, 14, 2943.

112. G. Liu, M. G. Humphrey, C. Zhang, Y. L. Zhao,
Self-assembled stereomutation with supramolecular chirality inversion. Chem. Soc. Rev. 2023, 52, 4443-4487.

111. Q. Zhou, C. Yang, Y. L. Zhao,
Dynamic organic room-temperature phosphorescent systems. Chem 2023, 9, 2446-2480.

110. T. He, Y. L. Zhao,
Covalent organic frameworks for energy conversion in photocatalysis. Angew. Chem. Int. Ed. 2023, 62, e202303086.

109. D. Wang, L. Zhang, C. Wang, Z. Cheng, W. Zheng, P. Xu, Q. Chen, Y. L. Zhao,
Missing-linker-confined single-atomic Pt nanozymes for enzymatic theranostics of tumor. Angew. Chem. Int. Ed. 2023, 62, e202217995.

108. J. Guo, J. Li, T. Wu, X. Peng, S. Wang, Z. Zhao, Y. Hua, B. Z. Tang, Y. L. Zhao,
Free radical-mediated intramolecular photocyclization of AIEgens based on 2,3-diphenylbenzo[b]thiophene S,S-dioxide. J. Am. Chem. Soc. 2023, 145, 7837–7844.

107. T. He, Z. Zhao, R. Liu, X. Liu, B. Ni, Y. Wei, Y. Wu, W. Yuan, H. Peng, Z. Jiang, Y. L. Zhao,
Porphyrin-based covalent organic frameworks anchoring Au single atoms for photocatalytic nitrogen fixation. J. Am. Chem. Soc. 2023, 145, 6057-6066.

106. X. Xiong, Y. Chen, Z. Wang, H. Liu, M. Le, C. Lin, G. Wu, L. Wang, X. Shi, Y.-G. Jia, Y. L. Zhao,
Polymerizable rotaxane hydrogels for three-dimensional printing fabrication of wearable sensors. Nat. Commun. 2023, 14, 1331.

105. A. K. Bindra, D. Wang, Y. L. Zhao,
Metal-organic frameworks meet polymers: from synthesis strategies to healthcare applications. Adv. Mater. 2023, 35, 2300700.

104. X. Shan, W. Chi, H. Jiang, Z. Luo, C. Qian, H. Wu, Y. L. Zhao,
Monomer and excimer emission in a conformational and stacking-adaptable molecular system. Angew. Chem. Int. Ed. 2023, 62, e202215652.

103. Y. Zhao, S. Song, D. Wang, H. Liu, J. Zhang, Z. Li, J. Wang, X. Ren, Y. L. Zhao,
Nanozyme-reinforced hydrogel as a H2O2-driven oxygenerator for enhancing prosthetic interface osseointegration in rheumatoid arthritis therapy. Nat. Commun. 2022, 13, 6758.

102. Y. Yu, Q. Cheng, X. Ji, H. Chen, W. Zeng, X. Zeng, Y. L. Zhao, L. Mei,
Engineered drug-loaded cellular membrane nanovesicles for efficient treatment of post-surgical cancer recurrence and metastasis. Sci. Adv. 2022, 8, add3599.

101. M. Chang, Z. Hou, M. Wang, D. Wen, C. Li, Y. Liu, Y. L. Zhao, J. Lin,
Cu single atom nanozyme based high-efficiency mild photothermal therapy through cellular metabolic regulation. Angew. Chem. Int. Ed. 2022, 61, e202209245.

100. C. Qian, L. Feng, W. L. Teo, J. Liu, W. Zhou, D. Wang, Y. L. Zhao,
Imine and imine-derived linkages in two-dimensional covalent organic frameworks. Nat. Rev. Chem. 2022, 6, 881-898.

99. C. You, X. Li, D. Wang, H. Chen, L. Liang, Y. Chen, Y. L. Zhao, H. Xiang,
Self-assembled aza-boron-dipyrromethene for ferroptosis-boosted sonodynamic therapy. Angew. Chem. Int. Ed. 2022, 61, e202210174.

98. J. Liu, F. You, B. He, Y. Wu, D. Wang, W. Zhou, C. Qian, G. Yang, G. Liu, H. Wang, Y. Guo, L. Gu, L. Feng, S. Li, Y. L. Zhao,
Directing the architecture of surface-clean Cu2O for CO electroreduction. J. Am. Chem. Soc. 2022, 144, 12410-12420.

97. L. Dai, M. Yao, Z. Fu, X. Li, X. Zheng, S. Meng, Z. Yuan, K. Cai, H. Yang, Y. L. Zhao,
Multifunctional metal-organic framework-based nanoreactor for starvation/oxidation improved indoleamine 2,3-dioxygenase-blockade tumor immunotherapy. Nat. Commun. 2022, 13, 2688.

96. Z. Wang, L. Gao, Y. Zheng, Y. Zhu, Y. Zhang, X. Zheng, C. Wang, Y. Li, Y. L. Zhao, C. Yang,
Four-in-one stimulus-responsive long-lived luminescent systems based on pyrene-doped amorphous polymers. Angew. Chem. Int. Ed. 2022, 61, e202203254.

95. J. Guo, C. Yang, Y. L. Zhao,
Long-lived organic room-temperature phosphorescence from amorphous polymer systems. Acc. Chem. Res. 2022, 55, 1160-1170.

94. Y. Chen, P. He, D. Jana, D. Wang, M. Wang, P. Yu, W. Zhu, Y. L. Zhao,
Glutathione-depleting organic metal adjuvants for effective NIR-II photothermal immunotherapy. Adv. Mater. 2022, 34, 2201706.

93. Y. Zhang, X. Chen, J. Xu, Q. Zhang, L. Gao, Z. Wang, L. Qu, K. Wang, Y. Li, Z. Cai, Y. L. Zhao, C. Yang,
Cross-linked polyphosphazene nanospheres boosting long-lived organic room temperature phosphorescence. J. Am. Chem. Soc. 2022, 144, 6107-6117.

92. F. Yang, R. Li, W. Wei, X. Ding, Z. Xu, P. Wang, G. Wang, Y. Xu, H. Fu, Y. L. Zhao,
Water-soluble doubly-strapped isolated perylene diimide chromophore. Angew. Chem. Int. Ed. 2022, 61, e202202491.

91. Y. Zhao, S. Song, X. Ren, J. Zhang, Q. Lin, Y. L. Zhao,
Supramolecular adhesive hydrogels for tissue engineering applications. Chem. Rev. 2022, 122, 5604-5640.

90. S. Dong, Y. Dong, B. Liu, J. Liu, S. Liu, Z. Zhao, W. Li, B. Tian, R. Zhao, F. He, S. Gai, Y. Xie, P. Yang, Y. L. Zhao,
Guiding transition metal-doped hollow cerium tandem nanozymes with elaborately regulated multi-enzymatic activities for intensive chemodynamic therapy. Adv. Mater. 2022, 34, 2107054.

89. J. Chen, L. Chen, Y. Wu, Y. Fang, F. Zeng, S. Wu, Y. L. Zhao,
A H2O2-activatable nanoprobe for diagnosing interstitial cystitis and liver ischemia-reperfusion injury via multispectral optoacoustic tomography and NIR-II fluorescent imaging. Nat. Commun. 2021, 12, 6870.

88. L. Gu, W. Ye, X. Liang, A. Lv, H. Ma, M. Singh, W. Jia, Z. Shen, Y. Guo, Y. Gao, H. Chen, D. Wang, Y. Wu, J. Liu, H. Wang, Y.-X. Zheng, Z. An, W. Huang, Y. L. Zhao,
Circularly polarized organic room temperature phosphorescence from amorphous copolymers. J. Am. Chem. Soc. 2021, 143, 18527-18535.

87. D. Wang, I. W. He, J. Liu, D. Jana, Y. Wu, X. Zhang, C. Qian, Y. Guo, X. Chen, A. K. Bindra, Y. L. Zhao,
Missing-linker-assisted artesunate delivery by metal-organic frameworks for synergistic cancer treatment. Angew. Chem. Int. Ed. 2021, 60, 26254-26259.

86. Y. Li, G. V. Baryshnikov, C. Xu, H. Ågren, L. Zhu, T. Yi, Y. L. Zhao, H. Wu,
Photoinduced radical emission in a coassembly system. Angew. Chem. Int. Ed. 2021, 60, 23842-23848.

85. D. Wang, Y. L. Zhao,
Single-atom engineering of metal-organic frameworks toward healthcare. Chem 2021, 7, 2635-2671.

84. Y. Zhang, Y. Su, H. Wu, Z. Wang, C. Wang, Y. Zheng, X. Zheng, L. Gao, Q. Zhou, Y. Yang, X. Chen, C. Yang, Y. L. Zhao,
Large-area, flexible, transparent, and long-lived polymer-based phosphorescence films. J. Am. Chem. Soc. 2021, 143, 13675-13685.

83. Z. Ma, Y. Zhang, X. Dai, W. Zhang, M. F. Foda, J. Zhang, Y. L. Zhao, H. Han,
Selective thrombosis of tumor for enhanced hypoxia-activated prodrug therapy. Adv. Mater. 2021, 33, 2104504.

82. Y. Wu, F. Zeng, Y. L. Zhao, S. Wu,
Emerging contrast agents for multispectral optoacoustic imaging and their biomedical applications. Chem. Soc. Rev. 2021, 50, 7924-7940.

81. X. Zhang, X. Chen, Y. Guo, G. Gao, D. Wang, Y. Wu, J. Liu, G. Liang, Y. L. Zhao, F.-G. Wu,
Dual gate-controlled therapeutics for overcoming bacterium-induced drug resistance and potentiating cancer immunotherapy. Angew. Chem. Int. Ed. 2021, 60, 14013-14021.

80. Y. Zhang, L. Gao, X. Zheng, Z. Wang, C. Yang, H. Tang, L. Qu, Y. Li, Y. L. Zhao,
Ultraviolet irradiation-responsive dynamic ultralong organic phosphorescence in polymeric systems. Nat. Commun. 2021, 12, 2297.

79. B. He, S. Jia, M. Zhao, Y. Wang, T. Chen, S. Zhao, Z. Li, Z. Lin, Y. L. Zhao, X. Liu,
General and robust photothermal heating-enabled high-efficiency photoelectrochemical water splitting. Adv. Mater. 2021, 33, 2004406.

78. Z. Li, X. Liu, G. Wang, B. Li, H. Chen, H. Li, Y. L. Zhao,
Photoresponsive supramolecular coordination polyelectrolyte as smart anticounterfeiting inks. Nat. Commun. 2021, 12, 1363.

77. H. Xiang, L. Zhao, L. Yu, H. Chen, C. Wei, Y. Chen, Y. L. Zhao,
Self-assembled organic nanomedicine enables ultrastable photo-to-heat converting theranostics in the second near infrared biowindow. Nat. Commun. 2021, 12, 218.

76. D. Wang, H. Wu, C. Wang, L. Gu, H. Chen, D. Jana, L. Feng, J. Liu, X. Wang, P. Xu, Z. Guo, Q. Chen, Y. L. Zhao,
Self-assembled single-site nanozyme for tumor-specific amplified cascade enzymatic therapy. Angew. Chem. Int. Ed. 2021, 60, 3001-3007.

75. C. Qian, W. Zhou, J. Qiao, D. Wang, X. Li, W. L. Teo, X. Shi, H. Wu, J. Di, H. Wang, G. Liu, L. Gu, J. Liu, L. Feng, Y. Liu, S. Y. Quek, K. P. Loh, Y. L. Zhao,
Linkage engineering by harnessing supramolecular interactions to fabricate 2D hydrazone-linked covalent organic framework platforms toward advanced catalysis. J. Am. Chem. Soc. 2020, 142, 18138-18149.

74. X. Liu, L. Xiao, J. Weng, Q. Xu, W. Li, C. Zhao, J. Xu, Y. L. Zhao,
Regulating the reactivity of black phosphorus via protective chemistry. Sci. Adv. 2020, 6, eabb4359.

73. Y. Liu, W. Zhou, W. L. Teo, K. Wang, L. Zhang, Y. Zeng, Y. L. Zhao,
Covalent-organic-framework-based composite materials. Chem 2020, 6, 3172-3202.

72. X. Zhang, X. Chen, J. Song, J. Zhang, X. Ren, Y. L. Zhao,
Size-transformable nanostructures: from design to biomedical applications. Adv. Mater. 2020, 32, 2003752.

71. D. Wang, D. Jana, Y. L. Zhao,
Metal-organic framework derived nanozymes in biomedicine. Acc. Chem. Res. 2020, 53, 1389-1400.

70. X. Wei, D. Zheng, M. Zhao, H. Chen, X. Fan, B. Gao, L. Gu, Y. Guo, J. Qin, J. Wei, Y. L. Zhao, G. Zhang,
Cross-linked polyphosphazene hollow nanosphere derived N/P doped porous carbon with single nonprecious metal atoms for oxygen reduction reaction. Angew. Chem. Int. Ed. 2020, 59, 14639-14646.

69. Y. Liu, S. Wang, X. Meng, Y. Ye, X. Song, Z. Liang, Y. L. Zhao,
Molecular expansion for constructing porous organic polymers with high surface areas and well-defined nanopores. Angew. Chem. Int. Ed. 2020, 59, 19487-19493.

68. G. Zuo, Y. Wang, W. L. Teo, A. Xie, Y. Guo, Y. Dai, W. Zhou, D. Jana, Q. Xian, W. Dong, Y. L. Zhao,
Ultrathin ZnIn2S4 nanosheets anchored on Ti3C2Tx MXene for photocatalytic H2 evolution. Angew. Chem. Int. Ed. 2020, 59, 11287-11292.

67. C. C. Xue, M. H. Li, Y. Zhao, J. Zhou, Y. Hu, K. Y. Cai, Y. L. Zhao, S. H. Yu, Z. Luo,
Tumor microenvironment-activatable Fe-doxorubicin preloaded amorphous CaCO3 nanoformulation triggers ferroptosis in target tumor cells. Sci. Adv. 2020, 6, eaax1346.

66. H. Wang, C. Qian, J. Liu, Y. Zeng, D. Wang, W. Zhou, L. Gu, H. Wu, G. Liu, Y. L. Zhao,
Integrating suitable linkage of covalent organic frameworks into covalently bridged inorganic/organic hybrids toward efficient photocatalysis. J. Am. Chem. Soc. 2020, 142, 4862-4871.

65. L. Gu, H. Wu, H. Ma, W. Ye, W. Jia, H. Wang, H. Chen, N. Zhang, D. Wang, C. Qian, Z. An, W. Huang, Y. L. Zhao,
Color-tunable ultralong organic room temperature phosphorescence from a multicomponent copolymer. Nat. Commun. 2020, 11, 944.

64. T. Zhang, X. Ma, H. Wu, L. Zhu, Y. L. Zhao, H. Tian,
Molecular engineering for metal-free amorphous room-temperature phosphorescent materials. Angew. Chem. Int. Ed. 2020, 59, 11206-11216.

63. Z. Wang, Y. Zhang, C. Wang, X. Zheng, Y. Zheng, L. Gao, C. Yang, Y. Li, L. Qu, Y. L. Zhao,
Color-tunable polymeric long-persistent luminescence based on polyphosphazenes. Adv. Mater. 2020, 32, 1907355.

62. D. Wang, H. Wu, S. Z. F. Phua, G. Yang, W. Q. Lim, L. Gu, C. Qian, H. Wang, Z. Guo, H. Chen, Y. L. Zhao,
Self-assembled single-atom nanozyme form enhanced photodynamic therapy treatment of tumor. Nat. Commun. 2020, 11, 357.

61. L. Zhao, J. Li, Y. Su, L. Yang, L. Chen, L. Qiang, Y. Wang, H. Xiang, H. P. Tham, J. Peng, Y. L. Zhao,
MTH1 inhibitor amplifies the lethality of reactive oxygen species to tumor in photodynamic therapy. Sci. Adv. 2020, 6, eaaz0575.

60. Y. Su, Y. Zhang, Z. Wang, W. Gao, P. Jia, D. Zhang, C. Yang, Y. Li, Y. L. Zhao,
Excitation-dependent long-life luminescent polymeric systems under ambient conditions. Angew. Chem. Int. Ed. 2020, 59, 9967-9971.

59. Y. Zhai, G. Liu, F. Jin, Y. Zhang, X. Gong, Z. Miao, J. Li, M. Zhang, Y. Cui, L. Zhang, Y. Liu, H. Zhang, Y. L. Zhao, Y. Zeng,
Construction of covalent-organic frameworks (COFs) from amorphous covalent organic polymers via linkage replacement. Angew. Chem. Int. Ed. 2019, 58, 17679-17683.

58. Y. Wang, S. Z. F. Phua, G. Dong, X. Liu, B. He, Q. Zhai, Y. Li, C. Zheng, H. Quan, Z. Li, Y. L. Zhao,
Structure tuning of polymeric carbon nitride for solar energy conversion: from nano to molecular scale. Chem 2019, 5, 2775-2813.

57. H. Wu, Z. Chen, W. Chi, B. A. Kaur, L. Gu, C. Qian, B. Wu, B. Yue, G. Liu, G. Yang, L. Zhu, Y. L. Zhao,
Structural engineering of luminogens with high emission efficiency both in solution and the solid state. Angew. Chem. Int. Ed. 2019, 58, 11419-11423.

56. P. Xing, Y. Li, S. Xue, S. Z. F. Phua, C. Ding, H. Chen, Y. L. Zhao,
Occurrence of chiral nanostructures induced by multiple hydrogen bonds. J. Am. Chem. Soc. 2019, 141, 9946-9954.

55. G. Liu, C. Zhou, W. L. Teo, C. Qian, Y. L. Zhao,
Self-sorting double-network hydrogels with tunable supramolecular handedness and mechanical property. Angew. Chem. Int. Ed. 2019, 58, 9366-9372.

54. H. Wu, Y. L. Zhao,
Colour-tunable ultralong emission. Nat. Photonics 2019, 13, 373-375.

53. D. Wang, H. Wu, W. Q. Lim, S. Z. F. Phua, P. Xu, Q. Chen, Z. Guo, Y. L. Zhao,
A mesoporous nanoenzyme derived from metal-organic frameworks with endogenous oxygen generation to alleviate tumor hypoxia for significantly enhanced photodynamic therapy. Adv. Mater. 2019, 31, 1901893.

52. L. Sun, R. Li, W. Zhan, Y. Yuan, X. Wang, X. Han, Y. L. Zhao,
Double-shelled hollow rods assembled from nitrogen/sulfur-codoped carbon coated indium oxide nanoparticles as excellent photocatalysts. Nat. Commun. 2019, 10, 2270.

51. G. Yang, S. Z. F. Phua, W. Q. Lim, R. Zhang, L. Feng, G. Liu, H. Wu, A. K. Bindra, D. Jana, Z. Liu, Y. L. Zhao,
A hypoxia-responsive albumin-based nanosystem for deep tumor penetration and excellent therapeutic efficacy. Adv. Mater. 2019, 31, 1901513.

50. H. Chen, X. Zeng, H. P. Tham, S. Z. F. Phua, W. Cheng, W. Zeng, H. Shi, L. Mei, Y. L. Zhao,
NIR-light-activated combination therapy with a precise ratio of photosensitizer and prodrug using a host-guest strategy. Angew. Chem. Int. Ed. 2019, 58, 7641-7646.

49. Z. Miao, G. Liu, Y. Cui, Z. Liu, J. Li, F. Han, Y. Liu, X. Sun, X. Gong, Y. Zhai, Y. L. Zhao, Y. Zeng,
A novel strategy for construction of covalent organic frameworks from nonporous covalent organic polymers. Angew. Chem. Int. Ed. 2019, 58, 4906-4910.

48. G. Yang, S. Z. F. Phua, A. K. Bindra, Y. L. Zhao,
Degradability and clearance of inorganic nanoparticles for biomedical applications. Adv. Mater. 2019, 31, 1805730.

47. G. Liu, J. Sheng, W. L. Teo, G. Yang, H. Wu, Y. Li, Y. L. Zhao,
Control on dimensions and supramolecular chirality of self-assemblies through light and metal ions. J. Am. Chem. Soc. 2018, 140, 16275-16283.

46. P. Xing, S. Z. F. Phua, X. Wei, Y. L. Zhao,
Programmable multicomponent self-assembly based on aromatic amino acids. Adv. Mater. 2018, 30, 1805175.

45. P. Xing, Y. L. Zhao,
Controlling supramolecular chirality in multicomponent self-assembled systems. Acc. Chem. Res. 2018, 51, 2324-2334.

44. Z. Liu, H. Zhang, Y. L. Zhao,
Pillararene-based self-assembled amphiphiles. Chem. Soc. Rev. 2018, 47, 5491-5528.

43. G. Liu, J. Sheng, H. Wu, C. Yang, G. Yang, Y. Li, R. Ganguly, L. Zhu, Y. L. Zhao,
Controlling supramolecular chirality of two-component hydrogels by J- and H-aggregation of building blocks. J. Am. Chem. Soc. 2018, 140, 6467-6473.

42. Y. Su, S. Z. F. Phua, Y. Li, X. Zhou, D. Jana, G. Liu, W. Q. Lim, W. K. Ong, C. Yang, Y. L. Zhao,
Ultralong room temperature phosphorescence from amorphous organic materials toward confidential information encryption and decryption. Sci. Adv. 2018, 4, eaas9732.

41. P. Xing, Y. Li, Y. Wang, P. Z. Li, H. Chen, S. Z. F. Phua, Y. L. Zhao,
Water binding mediated gelation/crystallization and thermosensitive superchirality. Angew. Chem. Int. Ed. 2018, 57, 7774-7779.

40. X. Zhang, Z. Luo, P. Yu, Y. Cai, Y. Du, D. Wu, S. Gao, C. Tan, Z. Li, M. Ren, T. Osipowicz, S. Chen, Z. Jiang, J. Li, Y. Huang, J. Yang, Y. Chen, C. Y. Ang, Y. L. Zhao, P. Wang, L. Song, X. Wu, Z. Liu, A. Borgna, H. Zhang,
Lithiation-induced amorphization of Pd3P2S8 for highly efficient hydrogen evolution. Nat. Catal. 2018, 1, 460-468.

39. Y. Wang, X. Liu, J. Liu, B. Han, X. Hu, F. Yang, Z. Xu, Y. Li, S. Jia, Z. Li, Y. L. Zhao,
Carbon quantum dot implanted graphite carbon nitride nanotubes: excellent charge separation and enhanced photocatalytic hydrogen evolution. Angew. Chem. Int. Ed. 2018, 57, 5765-5771.

38. P. Xing, H. Chen, H. Xiang, Y. L. Zhao,
Selective co-assembly of aromatic amino acids to fabricate hydrogels with light irradiation induced emission for fluorescent imprint. Adv. Mater. 2018, 30, 1705633.

37. C. Tan, L. Zhao, P. Yu, Y. Huang, B. Chen, Z. Lai, X. Qi, M. H. Goh, X. Zhang, S. Han, X. J. Wu, Z. Liu, Y. L. Zhao, H. Zhang,
Preparation of ultrathin two-dimensional TixTa1-xSyOz nanosheets as highly efficient photothermal agents. Angew. Chem. Int. Ed. 2017, 56, 7842-7846.

36. J. Liang, Z. Liang, R. Zou, Y. L. Zhao,
Heterogeneous catalysis in zeolites, mesoporous silica, and metal-organic frameworks. Adv. Mater. 2017, 29, 1701139.

35. X. Yao, Y. L. Zhao,
Three-dimensional porous graphene networks and hybrids for lithium-ion battery and supercapacitors. Chem 2017, 2, 171-200.

34. P. Xing, Y. L. Zhao,
Multifunctional nanoparticles self-assembled from small organic building blocks for biomedicine. Adv. Mater. 2016, 28, 7304-7339.

33. P. Z. Li, X. J. Wang, J. Liu, J. S. Lim, R. Zou, Y. L. Zhao,
A trazole-containing metal-organic framework as a highly effective and substrate size-dependent catalyst for CO2 conversion. J. Am. Chem. Soc. 2016, 138, 2142-2145.

32. Y. Zeng, R. Zou, Y. L. Zhao,
Covalent organic frameworks for CO2 capture. Adv. Mater. 2016, 28, 2855-2873.

31. L. Bai, Y. L. Zhao,
Interlocked moelcules - aqueous assembly. Nat. Chem. 2015, 7, 944-945.

30. K. T. Nguyen, Y. L. Zhao,
Engineering hybrid nanoparticles for on-demand diagnostics and therapeutics. Acc. Chem. Res. 2015, 48, 3016-3025.

29. P. Z. Li, X. J. Wang, S. Y. Tan, C. Y. Ang, H. Chen, J. Liu, R. Zou, Y. L. Zhao,
Clicked isoreticular metal-organic frameworks and their high performance on selective capture and separation of large organic molecules. Angew. Chem. Int. Ed. 2015, 54, 12748-12752.

28. P. Borah, S. Sreejith, P. Anees, N. V. Menon, Y. Kang, A. Ajayaghosh, Y. L. Zhao,
Near-IR squaraine dye-loaded gated periodic mesoporous organosilica for photo-oxidation of phenol in continuous-flow device. Sci. Adv. 2015, 1, e1500390.

27. X. Ma, Y. L. Zhao,
Biomedical applications of supramolecular systems based on host-guest interactions. Chem. Rev. 2015, 115, 7794-7839.

26. Y. Zeng, R. Zou, Z. Luo, H. Zhang, X. Yao, R. Zou, Y. L. Zhao,
Covalent organic frameworks formed with two types of covalent bonds based on orthogonal reactions. J. Am. Chem. Soc. 2015, 137, 1020-1023.

25. Y. Zhao, Z. Luo, M. Li, Q. Qu, X. Ma, S. H. Yu, Y. L. Zhao,
A preloaded amorphous calcium carbonate-doxorubicin@silica nanoreactor for pH-responsive delivery of anticancer drug. Angew. Chem. Int. Ed. 2015, 54, 919-922.

24. S. K. Maji, S. Sreejith, J. Joseph, M. Lin, T. He, Y. Tong, H. Sun, S. W. K. Yu, Y. L. Zhao,
Upconversion nanoparticles as a contrast agent for photoacoustic imaging in live mice. Adv. Mater. 2014, 26, 5633-5638.

23. L. Zhu, X. Li, S. Wu, K. T. Nguyen, H. Yan, H. Agren, Y. L. Zhao,
Chirality control in in-situ preparation of gold nanoparticle superstructures directed by a coordinatable organogelator. J. Am. Chem. Soc. 2013, 135, 9174-9180.

22. L. Zhu, X. Li, Q. Zhang, X. Ma, M. Li, H. Zhang, Z. Luo, H. Agren, Y. L. Zhao,
Unimolecular photoconversion of multicolor luminescence on hierarchical self-assemblies. J. Am. Chem. Soc. 2013, 135, 5175-5182.

21. H. Li, C. Cheng, P. R. McGonigal, A. C. Fahrenbach, M. Frasconi, W. G. Liu, Z. Zhu, Y. L. Zhao, C. Ke, J. Lei, R. M. Young, S. M. Dyar, D. T. Co, Y. W. Yang, Y. Y. Botros, W. A. Goddard, M. R. Wasielewski, R. D. Astumian, J. F. Stoddart,
Relative unidirectional translation in an artificial molecular assembly fueled by light. J. Am. Chem. Soc. 2013, 135, 18609-18620.

20. H. Li, Z. Zhu, A. C. Fahrenbach, B. M. Savoie, C. Ke, J. C. Barnes, J. Lei, Y. L. Zhao, L. M. Lilley, T. J. Marks, M. A. Ratner, J. F. Stoddart,
Mechanical bond-induced radical stabilization. J. Am. Chem. Soc. 2013, 135, 456-467.

19. S. Sreejith, X. Ma, Y. L. Zhao,
Graphene oxide wrapping on squaraine-loaded mesoporous silica nanoparticles for bioimaging. J. Am. Chem. Soc. 2012, 134, 17346-17349.

18. H. Yan, C. Teh, S. Sreejith, L. Zhu, A. Kwok, W. Fang, X. Ma, K. T. Nguyen, V. Korzh, Y. L. Zhao,
Functional mesoporous silica nanoparticles for photothermal-controlled drug delivery in vivo. Angew. Chem. Int. Ed. 2012, 51, 8373-8377.

17. P. Borah, X. Ma, K. T. Nguyen, Y. L. Zhao,
A vanadyl complex grafted to periodic mesoporous organosilica: a green catalyst for selective hydroxylation of benzene to phenol. Angew. Chem. Int. Ed. 2012, 51, 7756-7761.

16. L. Zhu, C. Y. Ang, X. Li, K. T. Nguyen, S. Y. Tan, H. Agren, Y. L. Zhao,
Luminescent color conversion on cyanostilbene functionalized quantum dots via in-situ photo-tuning. Adv. Mater. 2012, 24, 4020-4024.

15. C. Wang, Z. Li, D. Cao, Y. L. Zhao, J. W. Gaines, O. A. Bozdemir, M. W. Ambrogio, M. Frasconi, Y. Y. Botros, J. I. Zink, J. F. Stoddart,
Stimulated release of size-selected cargos in succession from mesoporous silica nanoparticles. Angew. Chem. Int. Ed. 2012, 51, 5460-5465.

14. M. W. Ambrogio, C. R. Thomas, Y. L. Zhao, J. I. Zink, J. F. Stoddart,
Mechanized silica nanoparticles: a new frontier in theranostic nanomedicine. Acc. Chem. Res. 2011, 44, 903-913.

13. H. Li, A. C. Fahrenbach, A. Coskun, Z. Zhu, G. Barin, Y. L. Zhao, Y. Y. Botros, J. P. Sauvage, J. F. Stoddart,
A light-stimulated moelcular switch driven by radical-radical interactions in water. Angew. Chem. Int. Ed. 2011, 50, 6782-6788.

12. Y. L. Zhao, Z. Li, S. Kabehie, Y. Y. Botros, J. F. Stoddart, J. I. Zink,
pH-Operated nanopistons on the surfaces of mesoporous silica nanoparticles. J. Am. Chem. Soc. 2010, 132, 13016-13025.

11. H. Meng, M. Xue, T. Xia, Y. L. Zhao, S. Kabehie, F. Tamanoi, J. F. Stoddart, J. I. Zink, A. E. Nel,
Autonomous in vitro anticancer drug release from mesoporous silica nanoparticles derivatized with pH-sensitive supramolecular nanovalves. J. Am. Chem. Soc. 2010, 132, 12690-12697.

10. Y. L. Zhao, J. F. Stoddart,
Noncovalent functionalization of single-walled carbon nanotubes. Acc. Chem. Res. 2009, 42, 1161-1171.

9. Q. Li, W. Zhang, Q. S. Mijanic, C. H. Sue, Y. L. Zhao, L. Liu, C. Knobler, J. F. Stoddart, O. M. Yaghi,
Docking in metal-organic frameworks. Science 2009, 325, 855-859.

8. D. Ferris, Y. L. Zhao, N. M. Khashab, H. A. Khatib, J. F. Stoddart, J. I. Zink,
Light-operated mechanized nanoparticles. J. Am. Chem. Soc. 2009, 131, 1686-1688.

7. Y. L. Zhao, L. Hu, G. Gruner, J. F. Stoddart,
A tunable photosensor. J. Am. Chem. Soc. 2008, 130, 16996-17003.

6. Y. L. Zhao, W. R. Dichtel, A. Trabolsi, S. Saha, I. Aprahamian, J. F. Stoddart,
A redox-switchable alpha-cyclodextrin-based [2]rotaxane. J. Am. Chem. Soc. 2008, 130, 11294-11296.

5. Y. L. Zhao, I. Aprahamian, A. Trabolsi, N. Erina, J. F. Stoddart,
Organogel formation by a cholesterol-stoppered bistable [2]rotaxane and its dumbbell precusor. J. Am. Chem. Soc. 2008, 130, 6348-6350.

4. Y. L. Zhao, L. Hu, J. F. Stoddart, G. Gruner,
Pyrenecyclodextrin-decorated single-walled carbon nanotube field-effect transistor as chemical sensor. Adv. Mater. 2008, 20, 1910-1915.

3. L. Hu, Y. L. Zhao, K. Ryu, C. Zhou, J. F. Stoddart, G. Gruner,
Light-induced charge transfer in CdSe-SWNT hybrids. Adv. Mater. 2008, 20, 939-946.

2. Y. Liu, L. Yu, Y. Chen, Y. L. Zhao, H. Yang,
Construction and DNA condensation of cyclodextrin-based polypseudorotaxanes with anthryl grafts. J. Am. Chem. Soc. 2007, 129, 10656-10657.

1. Y. Liu, Y. L. Zhao, H. Y. Zhang, H. B. Song,
Polymeric rotaxane constructed from the inclusion complex of beta-cyclodextrin and 4,4'-dipyridine by coordination with Ni(II) ions. Angew. Chem. Int. Ed. 2003, 42, 3260-3263.